Aspergillus nidulans mutants

Locus Designation : AcrA

Linkage group : IIL
Cultural requirement (property of mutant): Resistant to acriflavine

Locus Designation : aaX

Linkage group : VIR
Enzyme (or gene function) : allantoicase
Cultural requirement (property of mutant): cannot use allantoic acid as nitrogen source
Corresponding mutation in Neurospora: alc-1

Locus Designation : abaA

Linkage group : VIIIR
Cultural requirement (property of mutant): grows on minimal, is aconidial

Locus Designation : acrB

Linkage group : IIR
Cultural requirement (property of mutant): resistant to acriflavine

Locus Designation : actA

Linkage group : IIIL
Cultural requirement (property of mutant): resistant to cycloheximide (actidione)

Locus Designation : actB

Linkage group : IIR
Cultural requirement (property of mutant): resistant to cycloheximide (actidione)

Locus Designation : acuD

Linkage group : VR
Enzyme (or gene function) : isocitrate lyase
Cultural requirement (property of mutant): cannot use acetate as a carbon source
Corresponding mutation in Neurospora: acu-3

Locus Designation : acuE

Linkage group : IR
Enzyme (or gene function) : malate synthase
Cultural requirement (property of mutant): cannot use acetate as a carbon source
Corresponding mutation in Neurospora: acu-9

Locus Designation : acuF

Linkage group : VII
Enzyme (or gene function) : PEP carboxykinase
Cultural requirement (property of mutant): cannot use acetate as a carbon source
Corresponding mutation in Neurospora: acu-6

Locus Designation : acuG

Linkage group : VR
Enzyme (or gene function) : fructose-1,6-diphosphatase
Cultural requirement (property of mutant): cannot use acetate as a carbon source

Locus Designation : acuH

Linkage group : V
Enzyme (or gene function) : fructose-1,6-diphosphatase
Cultural requirement (property of mutant): cannot use acetate as a carbon source

Locus Designation : acuJ

Linkage group : IL
Enzyme (or gene function) : fructose-1,6-diphosphatase
Cultural requirement (property of mutant): cannot use acetate as a carbon source

Locus Designation : acuK

Linkage group : IVR
Enzyme (or gene function) : malic enzyme
Cultural requirement (property of mutant): cannot use acetate as a carbon source

Locus Designation : acuL

Linkage group : IVR
Enzyme (or gene function) : malic enzyme
Cultural requirement (property of mutant): cannot use acetate as a carbon source

Locus Designation : adA

Linkage group : IL
Enzyme (or gene function) : adenylosuccinase
Cultural requirement (property of mutant): requires adenine. No response to hypoxanthine. Response to adenine enhanced by addition of histidine
Corresponding mutation in Neurospora: ad-4

Locus Designation : adB

Linkage group : VIIIR
Enzyme (or gene function) : AMP succinate synthetase
Cultural requirement (property of mutant): requires adenine. No response to hypoxanthine. Response to adenine enhanced by addition of histidine
Corresponding mutation in Neurospora: ad-8

Locus Designation : adC

Linkage group : IIR
Enzyme (or gene function) : AIR carboxylase
Cultural requirement (property of mutant): requires adenine
Corresponding mutation in Neurospora: ad-3A?

Locus Designation : adD

Linkage group : IIR
Enzyme (or gene function) : AIR carboxylase
Cultural requirement (property of mutant): requires adenine
Corresponding mutation in Neurospora: ad-3B?

Locus Designation : adE

Linkage group : IR
Cultural requirement (property of mutant): requires adenine
Corresponding mutation in Neurospora: ad-7?

Locus Designation : adF

Linkage group : IR
Cultural requirement (property of mutant): requires adenine

Locus Designation : adG

Linkage group : IL
Cultural requirement (property of mutant): requires adenine
Corresponding mutation in Neurospora: ad-6ad-9

Locus Designation : adH

Linkage group : IIL
Cultural requirement (property of mutant): requires adenine
Corresponding mutation in Neurospora: ad-2?

Locus Designation : adI

Linkage group : IIIL
Cultural requirement (property of mutant): requires adenine, cannot use acetate as C source

Locus Designation : agaA

Linkage group : VIR
Enzyme (or gene function) : arginase
Cultural requirement (property of mutant):
Corresponding mutation in Neurospora: aga

Locus Designation : ahrA

Linkage group : VIIIR
Enzyme (or gene function) : asparaginase
Cultural requirement (property of mutant): resistant to 5 mM aspartic hydroxamate on 10 mM nitrate

Locus Designation : alX

Linkage group : IIIL
Enzyme (or gene function) : allantoinase
Cultural requirement (property of mutant): cannot use allantoin as N source
Corresponding mutation in Neurospora: aln-1

Locus Designation : alcA

Linkage group : VIIL
Enzyme (or gene function) : alcohol dehydrogenase I
Cultural requirement (property of mutant):

Locus Designation : alcC

Linkage group : VIIR
Enzyme (or gene function) : alcohol dehydrogenase III
Cultural requirement (property of mutant):

Locus Designation : aldA

Linkage group : VIIIR
Enzyme (or gene function) : aldehyde dehydrogenase
Cultural requirement (property of mutant):

Locus Designation : anA

Linkage group : IL
Cultural requirement (property of mutant): requires aneurin (thiamine)

Locus Designation : anB

Linkage group :
Cultural requirement (property of mutant): Requires aneurin (thiamine)

Locus Designation : apnA

Linkage group : IIL
Enzyme (or gene function) : asparaginase II
Cultural requirement (property of mutant): cannot use asparagine as a carbon source, barely uses it as a nitrogen source

Locus Designation : argA

Linkage group : VIR
Enzyme (or gene function) : arginosuccinase
Cultural requirement (property of mutant): requires arginine
Corresponding mutation in Neurospora: arg-10

Locus Designation : argB

Linkage group : IIIL
Enzyme (or gene function) : ornithine transcarbamylase
Cultural requirement (property of mutant): responds to citrulline or arginine
Corresponding mutation in Neurospora: arg-12

Locus Designation : argC

Linkage group : VIIIR
Enzyme (or gene function) : arginosuccinate synthetase
Cultural requirement (property of mutant): requires arginine
Corresponding mutation in Neurospora: arg-1

Locus Designation : argD

Linkage group : V
Cultural requirement (property of mutant): requires arginine

Locus Designation : benA

Linkage group : VIIIR
Enzyme (or gene function) : beta-tubulin
Cultural requirement (property of mutant): resistant to benomyl (Benlate) (approx. 10 ug/ml)
Corresponding mutation in Neurospora: Bml

Locus Designation : benB

Linkage group : IIR
Cultural requirement (property of mutant): resistant to benomyl (Benlate) (approx 2 ug/ml)

Locus Designation : benC

Linkage group : VIIR
Cultural requirement (property of mutant): resistant to benomyl (Benlate) (approx 2 ug/ml)

Locus Designation : biA1

Linkage group : IR
Cultural requirement (property of mutant): requires biotin
Corresponding mutation in Neurospora: none

Locus Designation : carA1

Linkage group : VIIR
Enzyme (or gene function) : ?
Cultural requirement (property of mutant): resistant to 100 ppm carboxin
Sensitive strains (and not resistant ones) show a difference in sensitivity
associated with carbon source. In an acetate medium carboxin is 7 X as
fungitoxic as on a glucose medium. VanTuyl (1975) Neth J Pl Path 81 122-123.

Locus Designation : carB2

Linkage group :VIIR
Enzyme (or gene function) : ?
Cultural requirement (property of mutant): resistant to 100 ppm carboxin
Sensitive strains (and not resistant ones) show a difference in sensitivity
associated with carbon source. In an acetate medium carboxin is 7 X as
fungitoxic as on a glucose medium. VanTuyl (1975) Neth J Pl Path 81 122-123.

Locus Designation :carC9

Linkage group :
Enzyme (or gene function) :
Cultural requirement (property of mutant): resistant to 100 ppm carboxin
Sensitive strains (and not resistant ones) show a difference in sensitivity
associated with carbon source. In an acetate medium carboxin is 7 X as
fungitoxic as on a glucose medium. VanTuyl (1975) Neth J Pl Path 81 122-123.

Locus Designation : choA

Linkage group : VIIR
Enzyme (or gene function) : phosphatidyl ethanolamine methyltransferase
Cultural requirement (property of mutant): responds to choline
Corresponding mutation in Neurospora: chol-1

Locus Designation : choC

Linkage group : VIIIR
Cultural requirement (property of mutant): responds to choline
Corresponding mutation in Neurospora: chol-2

Locus Designation : cnxA

Linkage group : VIIIR
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-7?

Locus Designation : cnxB

Linkage group : VIIIR
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-8?

Locus Designation : cnxC

Linkage group : VIIIR
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-9?

Locus Designation : cnxE

Linkage group : IIR
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-9?

Locus Designation : cnxF

Linkage group : VIIR
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-9?

Locus Designation : cnxG

Linkage group : VI
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-9?

Locus Designation : cnxH

Linkage group : IIIL
Enzyme (or gene function) : nitrate reductase, xanthine dehydrogenase
Cultural requirement (property of mutant): cannot use nitrate as a nitrogen source
Corresponding mutation in Neurospora: nit-9?

Locus Designation : cysA

Linkage group :
Enzyme (or gene function) : serine transacetylase
Cultural requirement (property of mutant): supresses methG. Causes cysteine auxotrophy in combination with mecB or mecC

Locus Designation : cysB

Linkage group :
Cultural requirement (property of mutant): Responds to cysteine, not to met or homocysteine when combined with mecB or mecC

Locus Designation : cysC

Linkage group :
Cultural requirement (property of mutant): Responds to cysteine, not to met or homocysteine when combined with mecB or mecC

Locus Designation : cysD

Linkage group :
Enzyme (or gene function) : homocysteine synthase
Cultural requirement (property of mutant): combined with cysC, causes requirement for O-acetyl serine

Locus Designation : drkA

Linkage group : VIIR
Cultural requirement (property of mutant): dark colored conidia

Locus Designation : drkB

Linkage group : IIR
Cultural requirement (property of mutant): dark colored conidia, suppressor of brlA12

Locus Designation : facA

Linkage group : VR
Enzyme (or gene function) : acetyl CoA synthetase
Cultural requirement (property of mutant): Resistant to fluoroacetate, cannot use acetate as a carbon source

Locus Designation : facB

Linkage group : VIIIR
Cultural requirement (property of mutant): fluoroacetate resistant, cannot use acetate as a carbon source

Locus Designation : facC

Linkage group : VIIIR
Cultural requirement (property of mutant): fluoroacetate resistant, cannot use acetate as a carbon source

Locus Designation : fpaA

Linkage group : IL
Cultural requirement (property of mutant): resistant to p-fluorophenylalanine, partial requirement for tyrosineresistance may be countered by excess phe

Locus Designation : fpaB

Linkage group : IL
Cultural requirement (property of mutant): resistant to p-fluorophenylalanine, which may be countered by excess phe

Locus Designation : fpaC

Linkage group : VII
Cultural requirement (property of mutant): resistant to p-fluorophenylalanine

Locus Designation : fpaD

Linkage group : III
Cultural requirement (property of mutant): resistant to p-fluorophenylalanine

Locus Designation : fpaI

Linkage group : IL
Cultural requirement (property of mutant): resistant to fluorophenylalanine

Locus Designation : frA

Linkage group : IVR
Cultural requirement (property of mutant): Poor growth, as measured by colony size vs. wt on plates, with fructose or sucrose as sole C source

Locus Designation : galA

Linkage group : IIIL
Enzyme (or gene function) : galactokinase
Cultural requirement (property of mutant): poor growth, as measured by colony size vs. wt on plates, when galactose is the sole C source

Locus Designation : galB

Linkage group : II
Cultural requirement (property of mutant): Grows more slowly than wt when galactose is the sole C source

Locus Designation : galC

Linkage group : VIII
Cultural requirement (property of mutant): Grows more slowly than wt when galactose is sole C source

Locus Designation : galD

Linkage group : IL
Enzyme (or gene function) : UDP-galactose pyrophosphorylase
Cultural requirement (property of mutant): Poor growth, compared with wt on plates, when galactose is sole C source

Locus Designation : galE

Linkage group : IIIL
Enzyme (or gene function) : galactokinase
Cultural requirement (property of mutant): Poor growth, compared with wt on plates, when galactose is sole C source

Locus Designation : galG

Linkage group : VIIIR
Cultural requirement (property of mutant): Cannot use galactose, suppresses brlA12

Locus Designation : gamA

Linkage group : I
Cultural requirement (property of mutant): cannot use galactose, resistant to 33 mM molybdate on 10 mM ammonium tartrate

Locus Designation : gamB

Linkage group : VIIIR
Cultural requirement (property of mutant): cannot use galactose, resistant to 33 mM molybdate on 10 mM ammonium tartrate

Locus Designation : gamC

Linkage group : ?
Cultural requirement (property of mutant): cannot use galactose, resistant to 33 mM molybdate on 10 mM ammonium tartrate

Locus Designation : gdhA

Linkage group : IIIL
Enzyme (or gene function) : NADP-glutamate dehydrogenase
Cultural requirement (property of mutant): requires alanine or glutamine or other amino source
Corresponding mutation in Neurospora: am

Locus Designation : gdhB

Linkage group : IV
Enzyme (or gene function) : NAD-glutamate dehydrogenase
Cultural requirement (property of mutant): grows poorly on 10 mM alanine as N source or 100 mM glutamate as sole N and C source

Locus Designation : hisA

Linkage group : IVL
Enzyme (or gene function) : AICAR isomerase?
Cultural requirement (property of mutant): Requires histidine

Locus Designation : hisB

Linkage group : I
Enzyme (or gene function) : imidazole glycerophosphate dehydratase
Cultural requirement (property of mutant): Requires histidine
Corresponding mutation in Neurospora: his-1

Locus Designation : hisC

Linkage group : VIIIR
Enzyme (or gene function) : imidazole acetol phosphate transaminase
Cultural requirement (property of mutant): requires histidine
Corresponding mutation in Neurospora: his-5

Locus Designation : hisG

Linkage group : II
Enzyme (or gene function) : ATP phosphoribosyl pyrophosphorylase
Cultural requirement (property of mutant): requires histidine
Corresponding mutation in Neurospora: his-2

Locus Designation : hisH

Linkage group : VIIIR
Enzyme (or gene function) : AICAR amidotransferase?
Cultural requirement (property of mutant): requires histidine

Locus Designation : hisJ

Linkage group : VII
Enzyme (or gene function) : regulatory?
Cultural requirement (property of mutant): requires histidine

Locus Designation : hxA

Linkage group : VR
Enzyme (or gene function) : xanthine dehydrogenase I
Cultural requirement (property of mutant): cannot use hypoxanthine as a nitrogen source
Corresponding mutation in Neurospora: xdh-1

Locus Designation : hxB

Linkage group : VII
Enzyme (or gene function) : xanthine dehydrogenase I and II
Cultural requirement (property of mutant): cannot use hypoxanthine as a nitrogen source

Locus Designation : ileA

Linkage group : IIR
Enzyme (or gene function) : threonine dehydratase
Cultural requirement (property of mutant): requires isoleucine
Corresponding mutation in Neurospora: ile-1

Locus Designation : imaA

Linkage group : VIIR
Cultural requirement (property of mutant): slight resistance to neomycin (4 mg/ml) and acriflavin (2 mg/ml)

Locus Designation : imaB

Linkage group : V
Cultural requirement (property of mutant): resistant to chloramphenicol (5 mg/ml), hypersensitive to acriflavin (0.5 mg/ml) and cycloheximide (0.5 mg/ml)

Locus Designation : imaC

Linkage group : IIR
Cultural requirement (property of mutant): resistant to chloramphenicol (5 mg/ml) and cycloheximide (2 mg/ml)

Locus Designation : imaD

Linkage group : VIIIR
Cultural requirement (property of mutant): Hypersensitive to cycloheximide (0.5 mg/ml)

Locus Designation : imaE

Linkage group : II
Cultural requirement (property of mutant): Resistant to chloramphenicol (5 mg/ml)

Locus Designation : imaG

Linkage group : III
Cultural requirement (property of mutant): Resistant to cycloheximide (2 mg/ml) May be allelic with actA

Locus Designation : imaH

Linkage group : III
Cultural requirement (property of mutant): Resistant to neomycin (4 mg/ml)

Locus Designation : inoA

Linkage group : IIR
Cultural requirement (property of mutant): requires inositol
Corresponding mutation in Neurospora: inl?

Locus Designation : inoB

Linkage group : IVR
Cultural requirement (property of mutant): requires inositol

Locus Designation : ivoA

Linkage group : IIIL
Cultural requirement (property of mutant): ivory colored conidiophores

Locus Designation : ivoB

Linkage group : VIIIR
Enzyme (or gene function) : phenol oxidase
Cultural requirement (property of mutant): ivory colored conidiophores

Locus Designation : lacA

Linkage group : VIR
Cultural requirement (property of mutant): Forms normal size but diffuse colonies when lactose is sole C source

Locus Designation : lacB

Linkage group : IIR
Cultural requirement (property of mutant): Forms normal size but diffuse colonies when lactose is sole C source

Locus Designation : luA

Linkage group : IL
Cultural requirement (property of mutant): requires leucine

Locus Designation : lysA

Linkage group : VIR
Cultural requirement (property of mutant): requires lysine

Locus Designation : lysB

Linkage group : VL
Cultural requirement (property of mutant): requires lysine, slight response to aminoadipate

Locus Designation : lysD

Linkage group : VIIR
Cultural requirement (property of mutant): responds to lysine or aminoadipate

Locus Designation : lysE

Linkage group : VR
Cultural requirement (property of mutant): requires lysine

Locus Designation : lysF

Linkage group : IR
Cultural requirement (property of mutant): responds to lysine or aminoadipate

Locus Designation : malA

Linkage group :
Cultural requirement (property of mutant): Forms normal size but diffuse colonies when maltose is sole C source

Locus Designation : manA

Linkage group : VIIIR
Enzyme (or gene function) : phosphomannose isomerase
Cultural requirement (property of mutant): cannot use mannose or glucose as a carbon source, but does grow on 0.9% glucose + 0.1 % mannose

Locus Designation : mauA

Linkage group : IVR
Enzyme (or gene function) : monoamine oxidase
Cultural requirement (property of mutant): cannot use methylamine or ethanolamine as N sources

Locus Designation : mauB

Linkage group : IIR
Enzyme (or gene function) : monoamine oxidase
Cultural requirement (property of mutant): cannot use methylamine or ethanolamine as N sources

Locus Designation : meaA

Linkage group : IVR
Cultural requirement (property of mutant): resistant to methylamine (100 mM) on nitrate media
Corresponding mutation in Neurospora: mea-1

Locus Designation : meaB

Linkage group : IIIL
Cultural requirement (property of mutant): resistant to methylamine (100 mM) on nitrate media

Locus Designation : mecA

Linkage group : IR
Enzyme (or gene function) : cystathionine beta-synthase
Cultural requirement (property of mutant): unable to grow on methionine + selenate

Locus Designation : mecB

Linkage group : IR
Enzyme (or gene function) : gamma-cystathionase
Cultural requirement (property of mutant): Unable to grow on methionine + selenate

Locus Designation : mecC

Linkage group : ?
Enzyme (or gene function) : methionine adenosyltransferase
Cultural requirement (property of mutant): unable to grow on methionine + selenate
Corresponding mutation in Neurospora: eth-1

Locus Designation : melA

Linkage group : VII
Cultural requirement (property of mutant): Excess melanin production

Locus Designation : melB

Linkage group : VIIR
Cultural requirement (property of mutant): reduced melanin production

Locus Designation : methB

Linkage group : VIR
Enzyme (or gene function) : cystathionine synthase
Cultural requirement (property of mutant): responds to cystathionine, homocysteine or methionine
Corresponding mutation in Neurospora: met-3,-7

Locus Designation : methE

Linkage group : VIIR
Enzyme (or gene function) : Homoserine transacetylase
Cultural requirement (property of mutant): requires methionine
Corresponding mutation in Neurospora: met-5

Locus Designation : methG

Linkage group : IVL
Enzyme (or gene function) : cystathionine B-lyase
Cultural requirement (property of mutant): responds to homocysteine or methionine, may adapt to grow on minimal after 2-3 days
Corresponding mutation in Neurospora: met-2

Locus Designation : methH

Linkage group : IIIL
Enzyme (or gene function) : methyl tetrahydrofolate homocysteine transmethylase
Cultural requirement (property of mutant): requires methionine, may adapt and grow on minimal after 2-3 days
Corresponding mutation in Neurospora: met-8

Locus Designation : niaD

Linkage group : VIIIR
Enzyme (or gene function) : nitrate reductase
Cultural requirement (property of mutant): Cannot use nitrate as a nitrogen source, should be resistant to chlorate, unable to use glutamate as an N source
Corresponding mutation in Neurospora: nit-3

Locus Designation : nicA

Linkage group : VL
Cultural requirement (property of mutant): Requires nicotinic or anthranilic acid

Locus Designation : nicB

Linkage group : VIIR
Cultural requirement (property of mutant): Requires nicotinic or anthranilic acid or tryptophan
Corresponding mutation in Neurospora: nt?

Locus Designation : nicC

Linkage group : VIR
Cultural requirement (property of mutant): Requires nicotinic acid

Locus Designation : niiA

Linkage group : VIIIR
Enzyme (or gene function) : nitrite reductase
Cultural requirement (property of mutant): Cannot use nitrite as a nitrogen source
Corresponding mutation in Neurospora: nit-6

Locus Designation : nirA

Linkage group : VIIIR
Enzyme (or gene function) : transcription activator?
Cultural requirement (property of mutant): cannot use nitrite or nitrate
Corresponding mutation in Neurospora: nit-4

Locus Designation : oliA

Linkage group : mito.
Enzyme (or gene function) : ATP synthetase
Cultural requirement (property of mutant): resistant to oligomycin

Locus Designation : oliC

Linkage group : VIIR
Cultural requirement (property of mutant): resistant to oligomycin
Corresponding mutation in Neurospora: oli

Locus Designation : ornA

Linkage group : IVR
Enzyme (or gene function) : N-acetyl glutamate kinase + N-acetylglutamate semialdehyde dehydrogenase
Cultural requirement (property of mutant): Requires ornithine, citrulline or arginine
Corresponding mutation in Neurospora: arg-6

Locus Designation : ornB

Linkage group : VIIIR
Enzyme (or gene function) : see ornA
Cultural requirement (property of mutant): Requires ornithine, citrulline or arginine
Corresponding mutation in Neurospora: arg-6

Locus Designation : ornC

Linkage group : IIIR
Enzyme (or gene function) : N-acetyl ornithine deacetylase
Cultural requirement (property of mutant): Requires ornithine, citrulline or arginine
Corresponding mutation in Neurospora: arg-4

Locus Designation : pabaA

Linkage group : IR
Cultural requirement (property of mutant): Requires p-aminobenzoate

Locus Designation : pabaB

Linkage group : IVR
Cultural requirement (property of mutant): Requires p-aminobenzoate

Locus Designation : pacA

Linkage group : IV
Enzyme (or gene function) : acid phosphatase
Cultural requirement (property of mutant): phosphatase activity lacking at pH 4.8, normal at pH 8.3

Locus Designation : pacC

Linkage group : VIR
Enzyme (or gene function) : acid phosphatase
Cultural requirement (property of mutant): phosphatase activity is reduced at pH 4.8 (some activity at 25 degrees, none at 35), normal at pH 8.2
Corresponding mutation in Neurospora: pho-3?

Locus Designation : palA

Linkage group : IIIL
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 8.2, but is greater than wt at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palB

Linkage group : VIIR
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is generally lacking at pH 8.2 but is greater than normal at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palC

Linkage group : IVR
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 8.2 but is greater than wt at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palD

Linkage group : VIIR
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 8.3 but normal at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palE

Linkage group : VIIIL
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 8.3 but is greater than wt at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palF

Linkage group : VIIR
Enzyme (or gene function) : alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 8.3 but is greater than wt at pH 4.8
Corresponding mutation in Neurospora: pho-2?

Locus Designation : palcA

Linkage group : IIL
Enzyme (or gene function) : acid and alkaline phosphatase
Cultural requirement (property of mutant): no phosphatase activity at pH 4.8 or 8.3 Shows partial activity at either pH at 25 degrees
Corresponding mutation in Neurospora: nuc-1?

Locus Designation : palcC

Linkage group : VIIIR
Enzyme (or gene function) : acid and alkaline phosphatase
Cultural requirement (property of mutant): phosphatase activity is lacking at pH 4.8 and greatly reduced at pH 8.3
Corresponding mutation in Neurospora: nuc-1?

Locus Designation : pantoA

Linkage group : VIIIR
Enzyme (or gene function) : pantothenate synthetase
Cultural requirement (property of mutant): Requires pantothenate
Corresponding mutation in Neurospora: pan-1?

Locus Designation : pantoB

Linkage group : VIIR
Cultural requirement (property of mutant): Requires pantothenate

Locus Designation : pantoC

Linkage group : IIIL
Cultural requirement (property of mutant): Requires pantothenate

Locus Designation : pdhA

Linkage group : IR
Enzyme (or gene function) : lipoate acetyltransferase
Cultural requirement (property of mutant): Requires acetate, may be inhibited by sucrose
Corresponding mutation in Neurospora: ace-4

Locus Designation : pdhB

Linkage group : VL
Enzyme (or gene function) : beta subunit of pyruvate decarboxylase
Cultural requirement (property of mutant): requires acetate, may be inhibited by sucrose
Corresponding mutation in Neurospora: ace-2,-3

Locus Designation : pdhC

Linkage group : VIIIL
Enzyme (or gene function) : alpha subunit of pyruvate decarboxylase
Cultural requirement (property of mutant): requires acetate, may be inhibited by sucrose
Corresponding mutation in Neurospora: ace-3,-2

Locus Designation : phenA

Linkage group : IIIR
Enzyme (or gene function) : Prephenate dehydratase
Cultural requirement (property of mutant): Requires phenylalanine
Corresponding mutation in Neurospora: phe-2

Locus Designation : phenB

Linkage group : VIIR
Cultural requirement (property of mutant): Has a partial requirement for phenylalanine

Locus Designation : pkiA

Linkage group : V
Enzyme (or gene function) : pyruvate kinase
Cultural requirement (property of mutant): Require acetate or alanine as a carbon source
Corresponding mutation in Neurospora: ace-8

Locus Designation : pppA

Linkage group : VIII
Enzyme (or gene function) : transaldolase
Cultural requirement (property of mutant): Cannot use xylose or arabinose as carbon sources

Locus Designation : pppB

Linkage group : III
Cultural requirement (property of mutant): Cannot use xylose or arabinose as carbon sources

Locus Designation : proA

Linkage group : IL
Cultural requirement (property of mutant): Responds best to proline; also to ornithine, citrulline or arginine
Corresponding mutation in Neurospora: pro-3

Locus Designation : proB

Linkage group : IL
Cultural requirement (property of mutant): Responds best to proline; also to ornithine, citrulline or arginine
Corresponding mutation in Neurospora: pro-4

Locus Designation : puA

Linkage group : IIR
Enzyme (or gene function) : ornithine decarboxylase
Cultural requirement (property of mutant): Requires putrescine
Corresponding mutation in Neurospora: spe-1

Locus Designation : punA

Linkage group : IIR
Cultural requirement (property of mutant): Grows poorly on putrescine as a nitrogen source

Locus Designation : pycA

Linkage group : V
Enzyme (or gene function) : pyruvate carboxylase
Cultural requirement (property of mutant): Prefers acetate or glutamate + fructose as carbon sources
Corresponding mutation in Neurospora: suc

Locus Designation : pyrD

Linkage group : VIIIR
Enzyme (or gene function) : dehydro-orotase
Cultural requirement (property of mutant): Responds to uridine
Corresponding mutation in Neurospora: pyr-6

Locus Designation : pyrE

Linkage group : IL
Enzyme (or gene function) : dehydro-orotate dehydrogenase
Cultural requirement (property of mutant): Responds to uridine
Corresponding mutation in Neurospora: pyr-1

Locus Designation : pyrG

Linkage group : IL
Enzyme (or gene function) : orotidine monophosphate decarboxylase
Cultural requirement (property of mutant): Optimal supplementation is 2.5 mg/ml (10 mM) each of uridine + uracil
Corresponding mutation in Neurospora: pyr-4

Locus Designation : pyroA

Linkage group : IVR
Cultural requirement (property of mutant): Responds to pyridoxine

Locus Designation : pyroB

Linkage group : IL
Cultural requirement (property of mutant): Responds to pyridoxine
Corresponding mutation in Neurospora: pdx-1?

Locus Designation : rA

Linkage group : IL
Cultural requirement (property of mutant): phosphatase activity is normal at pH 4.8 but greater than wt at pH 8.3

Locus Designation : riboA1

Linkage group : IL
Cultural requirement (property of mutant): Requires riboflavin

Locus Designation : riboB

Linkage group : VIIIR
Cultural requirement (property of mutant): Requires riboflavin. Confers self-sterility

Locus Designation : riboC

Linkage group : V
Cultural requirement (property of mutant): Requires riboflavin

Locus Designation : riboD

Linkage group : VR
Cultural requirement (property of mutant): requires riboflavin on nitrate media

Locus Designation : riboE

Linkage group : IIR
Cultural requirement (property of mutant): requires riboflavin

Locus Designation : riboF

Linkage group : I
Cultural requirement (property of mutant): Requires riboflavin

Locus Designation : sA

Linkage group : IIIL
Enzyme (or gene function) : PAPS reductase
Cultural requirement (property of mutant): responds to sulfite, resistant to 0.5 mM selenate
Corresponding mutation in Neurospora: cys-5

Locus Designation : sB

Linkage group : VIR
Enzyme (or gene function) : deficient in sulfate uptake
Cultural requirement (property of mutant): resistant to 10 mM chromate, 1 mM selenate
Corresponding mutation in Neurospora: cys-12

Locus Designation : sC

Linkage group : IIIL
Enzyme (or gene function) : ATP sulfurylase
Cultural requirement (property of mutant): responds to sulfite, resistant to 1 mM selenate on medium containing 0.1 mM methionine
Corresponding mutation in Neurospora: cys-11

Locus Designation : sD

Linkage group : VIIIR
Enzyme (or gene function) : adenosine 5 phosphosulfate kinase
Cultural requirement (property of mutant): responds to sulfite, more sensitive than wt to 0.25 mM selenate

Locus Designation : sE

Linkage group : VIIIR
Enzyme (or gene function) : PAPS reductase
Cultural requirement (property of mutant): responds to sulfite, more sensitive than wt to 0.25 mM selenate
Corresponding mutation in Neurospora: cys-5

Locus Designation : sF

Linkage group : VIIR
Cultural requirement (property of mutant): responds to thiosulfate, leaky

Locus Designation : sbA

Linkage group : VIR
Cultural requirement (property of mutant): Poor growth, as measured colony size vs wt on plates, on sorbitol as sole C source

Locus Designation : sltA

Linkage group : VIR
Cultural requirement (property of mutant): Inhibited by 0.5 M NaCl in medium

Locus Designation : sorA

Linkage group : I
Cultural requirement (property of mutant): Resistant to sorbose when glycerol is C source, also resistant to deoxyglucose

Locus Designation : sorB

Linkage group : IIIL
Enzyme (or gene function) : phosphoglucomutase
Cultural requirement (property of mutant): forms small colonies
Corresponding mutation in Neurospora: rg-1?

Locus Designation : spsA

Linkage group : III
Cultural requirement (property of mutant): Can use 0.06 mM spermidine in place of putrescine, but is inhibited by 6 mM spermidine

Locus Designation : stuA

Linkage group : IL
Cultural requirement (property of mutant): stunted conidiophores

Locus Designation : sucA

Linkage group : ?
Cultural requirement (property of mutant): cannot use succinate as a carbon source

Locus Designation : sulA

Linkage group : IL
Cultural requirement (property of mutant): resistant to sulphanilamide

Locus Designation : tamA

Linkage group : VI
Cultural requirement (property of mutant): resistant to 5 mM thiourea or 0.32 mM aspartate hydroxamate when 10 mM alanine is the N source

Locus Designation : telA

Linkage group : VII
Cultural requirement (property of mutant): mound shaped colony

Locus Designation : thiA

Linkage group : IIR
Cultural requirement (property of mutant): Responds to thiazole
Corresponding mutation in Neurospora: thi-3?

Locus Designation : trypA

Linkage group : IIR
Enzyme (or gene function) : anthranilate synthetase
Cultural requirement (property of mutant): responds to anthranilate, indole or tryptophan
Corresponding mutation in Neurospora: trp-2

Locus Designation : trypB

Linkage group : IL
Enzyme (or gene function) : tryptophan synthetase
Cultural requirement (property of mutant): Requires tryptophan
Corresponding mutation in Neurospora: trp-3

Locus Designation : trypC

Linkage group : VIIIR
Enzyme (or gene function) : Anthranilate synthatase, phosphoribosyl transferase, IGP synthetase
Cultural requirement (property of mutant): some respond to anthranilate, others only to indole or tryptophan Optimal concentration of tryptophan is 4 mM
Corresponding mutation in Neurospora: trp-1

Locus Designation : trypD

Linkage group : IIR
Enzyme (or gene function) : anthranilate phosphoribosyl transferase
Cultural requirement (property of mutant): responds to indole or tryptophan
Corresponding mutation in Neurospora: trp-4

Locus Designation : uaX

Linkage group : VI
Cultural requirement (property of mutant): slow growth when uric acid is the N source

Locus Designation : uaY

Linkage group : VIIIR
Enzyme (or gene function) : xanthine dehydrogenase and urate oxidase regulation
Cultural requirement (property of mutant): Cannot use uric acid as N source

Locus Designation : uaZ

Linkage group : IL
Enzyme (or gene function) : urate oxidase
Cultural requirement (property of mutant):

Locus Designation : uapA

Linkage group : IR
Enzyme (or gene function) : uric acid-xanthine permease
Cultural requirement (property of mutant):

Locus Designation : ureA

Linkage group : VIIIR
Enzyme (or gene function) : urea uptake
Cultural requirement (property of mutant): Cannot use urea as N source, resistant to thiourea

Locus Designation : ureB

Linkage group : VIIIR
Enzyme (or gene function) : urease
Cultural requirement (property of mutant): Cannot use urea as N source, no urease activity
Corresponding mutation in Neurospora: ure-2

Locus Designation : ureC

Linkage group : VII
Enzyme (or gene function) : urease
Cultural requirement (property of mutant): Cannot use urea as N source, no urease activity
Corresponding mutation in Neurospora: ure-3

Locus Designation : ureD

Linkage group : VIIIR
Enzyme (or gene function) : urease
Cultural requirement (property of mutant): Cannot use urea as N source. No urease activity
Corresponding mutation in Neurospora: ure-4

Locus Designation : wA

Linkage group : IIL
Cultural requirement (property of mutant): white conidia

Locus Designation : wetA

Linkage group : VIIR
Cultural requirement (property of mutant): white conidia autolyze, giving wet appearance

Locus Designation : xprD

Linkage group : IIIR
Enzyme (or gene function) : regulation of nitrogen metabolism
Cultural requirement (property of mutant): =areA
Corresponding mutation in Neurospora: nit-2

Locus Designation : yA

Linkage group : IR
Enzyme (or gene function) : p-diphenol oxidase
Cultural requirement (property of mutant): yellow conidia

Return to the FGSC main page