INFORMATION ON INDIVIDUAL LOCI

Gathered in this section is information on each established gene locus and on chromosomal features such as centromeres, tips, and the nucleolus organizer. Entries are arranged alphabetically by symbol. Some categories of genes are prefaced by a generic entry which concerns the entire group (e.g., al, arg, mus, rec, Transport mutants). Synonyms or abandoned symbols are cross-referenced to the current or preferred symbol. Chromosome rearrangements are listed only if they have been used to establish gene order or to map chromosome tips and centromeres.

Within each entry for a gene locus, the name follows the symbol. Linkage data are then given, including linkage group, arm (if known), and location relative to other loci. Representative recombination values are given as percent crossovers among random ascospores unless otherwise specified. Ranges are given. Many of these cannot be attributed to sampling error, but are thought to reflect differences in genes having locally specific effects on recombination (see rec). The phenotype is described in the second paragraph. Information is given concerning such attributes as enzyme deficiency, dominance, interaction with other genes, fertility, properties of specific alleles, stability, scoring, technical applications, and alternative names.

In the paragraph on linkage we have cited mainly the most recent, definitive datum sources that establish location of a gene relative to its immediate neighbors. In addition, we have cited the earliest publication that originally assigned the locus to its linkage group; this reference is set in italics. Where an italicized reference number is separated from the previous sentence by a period, it signifies that the reference has not contributed to the recombination data given and is cited solely because it first assigned the gene to a linkage group. It is regrettable that all those investigators whose earlier data indicated gene order less precisely but provided intermediate steps that were essential for deriving the current maps cannot be credited. Substantial mapping data have been published in references 47, 156, 158, 219, 4827 633, 692, 698, 789, 812, 814, 816, 818, 991, 1012, and 1036.

Similarly, in the paragraph on phenotype, space limitations preclude citing all the important references for loci that have been studied extensively; the references selected should lead the reader to other significant literature. Some reference numbers in parentheses are set off from the previous sentence by a period. This signifies that their relevance is not limited to the immediately preceding sentence.

When "PB" is used in place of a reference number, the source referred to is D. D. Perkins and M. Bjorkman, unpublished data.

Allele numbers are given only when there is a question about allelism, when two alleles differ significantly in phenotype, or sometimes when a mutant was referred to only by allele number in the references cited. Allele numbers of other mutant strains can be found in FGSC listings or in the references given. When a particular mutant gene has not yet been definitely assigned to a locus, the allele number may be given in parentheses following an appropriate gene symbol, e.g., nuh(23), cyt(289-56). Where allele numbers are not specified, information in an entry is for alleles used in the references cited. A table relating allele numbers to locus symbols is given on p. 31-33 of reference 47.

A few entries (e.g., pts-1, sit) concern chromosomal genes that have not yet been mapped but that probably involve previously unidentified loci.

Theses and abstracts have usually been cited only if they contain pertinent information that has not been published or adequately documented in a published reference.


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Last modified 4/24/96 KMC