Gene: adenine-5 IL
adenine-5
locus: ad-5
locus_name: adenine-5
organism_type: B
chromosome_number: I
chromosome_side: L
link_group: IL
cultural_requirements: IL. Between phe-1 and arg-1 (1%) (816; H.B. Howe, Jr., personal communication). (482) Uses adenine or hypoxanthine (682) (Fig. 8). Accumulates AICAR (81, 904) and SAICAR (81). Some mutants are stimulated by histidine and may not grow on hypoxanthine unless histidine is present; others may be inhibited by histidine (393; M.E. Case, personal communication). Produces some purple pigment, but less than ad-3A and ad-3Bmutants (526). Called complementation group J. Evidence, apparently enzymatic, given in reference 120 suggests that some ad-5 mutants lack both AICAR formyltransferase and inosine 5'-monophosphate cyclohydrolase, but apparently other ad-5 mutants lack only the formyltransferase. Indirect evidence (902, 904) suggests that strains carrying ad-5 allele Y112M192 are blocked at the formyltransferase step.
enzyme_id: 10
Enzyme: AICAR formyltransferase
anid_name: none
near_l: phe-1
near_r: arg-1 (1%)
neu_name:
supplement: adenine or hypoxanthine
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #15 | ad-5 | Neurospora crassa |
| FGSC #235 | ad-5 his-2 al-1 pt ylo-1 | Neurospora crassa |
| FGSC #246 | ad-5 his-2 cr-1 | Neurospora crassa |
| FGSC #256 | ad-5 nic-2 thi-1;cot-1 | Neurospora crassa |
| FGSC #678 | Has been replaced by strain number: 3459 | Neurospora crassa |
| FGSC #679 | ad-5 | Neurospora crassa |
| FGSC #3458 | ad-5 | Neurospora crassa |
| FGSC #3459 | ad-5 | Neurospora crassa |
| FGSC #5435 | ad-5 rg-1 cr-1 | Neurospora crassa |
| FGSC #8127 | ad-5 | Neurospora crassa |
| FGSC #8129 | ad-5 | Neurospora crassa |
| FGSC #8193 | ad-5 | Neurospora crassa |
References
