Gene: adenine-8 VIL
adenine-8
locus: ad-8
locus_name: adenine-8
organism_type: B
chromosome_number: VI
chromosome_side: L
link_group: VIL
cultural_requirements: VIL. Right of ser-6 (15%) and het-8 (12%). Left of aro-6 (8%) and cpl-1(6 to 11%) (437, 510, 730, PB). Requires adenine; cannot use hypoxanthine (526). Lacks adenylosuccinate synthase (511) (Fig. 8). Fine-structure mapping and intralocus complementation (510-512). Has little hypoxanthine uptake and little hypoxanthine phosphoribosyltransferase; both these effects are partly counteracted in ad-1 ad-8 double mutants (903). Little hypoxanthine phosphoribosyltransferase is also found in mep(3) and mep(10)mutants, q.v. Used to study purine transport (787, 903, and references therein). Called complementation group E.
enzyme_id: 54
Enzyme: adenylosuccinate synthase
anid_name: adB
near_l: ser-6 (15%) and het-8 (12%)
near_r: aro-6 (8%) and cpl-1(6 to 11%)
neu_name:
supplement: adenine
image_url:
Strains
References
