Gene: ribosome production-1 IIR
ribosome production-1
locus: rip-1
locus_name: ribosome production-1
organism_type: B
chromosome_number: II
chromosome_side: R
link_group: IIR
cultural_requirements: IIR. Linked to un-15 (1%); right of fl and trp-3 (6 to 9%). (PB). Conditional defect in production of 60S ribosomal subunits (622). At the restrictive temperature (37 C), RNA synthesis is affected first and then protein synthesis; 60S cytosolic ribosomal subunits are underaccumulated, and relatively little 25S rRNA is produced (618, 620, 622; P.J. Russell, personal communication). Defective ribosome biosynthesis at high temperatures is attributed to a defect in rRNA processing (622). Attains 2.4% of the wild-type growth rate at 35°C and 80% at 25°C (P.J. Russell, personal communication). Scored as an irreparable heat-sensitive un mutant (see un). Good fertility, growth, and viability make rip-1preferable to un-15 as a marker for the right end of II. The onginal strain carrying both rip-1 and inl (89601) (382, PB). was called 4M(t). The rip-1 allele in this strain was originally called 1(t).
enzyme_id:
anid_name:
near_l: fl and trp-3 (6 to 9%)
near_r: Linked to un-15 (1%)
neu_name:
supplement:
image_url:
Strains
References
