Gene: uracil uptake-5 IV
uracil uptake-5
locus: uc-5
locus_name: uracil uptake-5
organism_type: B
chromosome_number: IV
chromosome_side:
link_group: IV
cultural_requirements: IV. Right of cot-1 (32%) (126). (1139, 1141). Apparently defective in transport of pyrimidine bases (Fig. 23). Unable to use any free pyrimidine base to support the growth of the pynmidine auxotroph pyr-1, although it can use both ribose- and deoxyribose-nucleosides (1141). Resistant to 5-fluorouracil (126). The pyr-1 uc-5 double mutant has been used to study uptake inhibition of structural analogs (225). Selected by inability to use uracil to supplement pyr auxotrophs, or as 5-fluorouracil resistant on ammonia-free minimal medium (126). Uracil uptake is decreased by NH3 (629) or by other good nitrogen sources, and by a nit-2 mutation (128). Called tru.
enzyme_id:
anid_name:
near_l: cot-1 (32%)
near_r:
neu_name:
supplement:
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #2201 | uc-5 pyr-1 | Neurospora crassa |
References
