UV photoreactivation-1

locus: upr-1

locus_name: UV photoreactivation-1

organism_type: B

chromosome_number: I

chromosome_side: L

link_group: IL

cultural_requirements: IL. Between mt (2%) and arg-1 (7%) (1094). Sensitive to UV (273, 1096), nitrous acid (1094), ionizing radiation (940), and nitrosoguanidine, 4-nitroquinoline 1-oxide, and ICR-170 (509). Insensitive or marginally sensitive to methylmethane sulfonate (536). Unable to excise dimers (1164). Normal spontaneous mutation (275). High UV-induced mutation (273). For mutation induction by other agents, see references 509 and 940. Defective photoreactivation in vivo, but photoreactivation enzyme functions in vitro (1094). No homozygous effect on meiosis or crossing over (1094). Recessive in heterokaryons (979). Double mutant upr-1;uvs-3 is more sensitive than either single mutant (1095). Double mutant upr-1;uvs-2 is no more sensitive than the uvs-2 single mutant (506).

enzyme_id: 202

Enzyme: none

anid_name:

near_l: mt (2%)

near_r: arg-1 (7%)

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #1703	upr-1 cr-1 rg-1;pe fl;uvs-1;met(331)	Neurospora crassa
FGSC #1705	upr-1 cr-1 rg-1;pe fl;met(331)	Neurospora crassa
FGSC #2288	upr-1;uvs-3	Neurospora crassa
FGSC #2289	upr-1;uvs-3	Neurospora crassa
FGSC #4171	upr-1	Neurospora crassa
FGSC #4772	his-2 ad-3A ad-3B nic-2;ad-2;upr-1;inl	Neurospora crassa
FGSC #4935	al-2;cot-1;pan-2;upr-1	Neurospora crassa

References

Authors	Title	Year
De Serres, F. J.	Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurospora crassa. II. Comparison ofdose-response curves for inactivation and mutation induced aby UV.	1980
De Serres, F. J. , H. Inoue, and M. E. Schpbach.	Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains ofNeurospora crassa. I. Development of isogenic strains and spontaneous mutability.	1980
Inoue, H. , R. C. Harvey, D. F. Callen, and F. J. de Serres.	Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains ofNeurospora crassa. V. Comparison of dose-response curves of single- and double-mutant strains with wild type.	1981
Inoue, H. , T. M. Ong, and F. J. de Serres.	Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurosporacrassa. IV. Comparison of dose-response curves for MNNG, 4NQO and ICR-170 induced inactivation and mutation-induction.	1981
Kafer, E.	Sensitivity to methyl-methane sulfonate (MMS) in Neurospora.	1978
Schpbach, M. E. and F. J. de Serres.	Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurospora crassa. III. Comparison of dose-response curves for inactivation and mutation induced by gamma rays.	1981
Shelby, M. D. , F. J. de Serres, and G. J. Stine.	Ultraviolet-inactivation of conidia from heterokaryons of Neurospora crassa containingUV-sensitive mutations.	1975
Tuveson, R. W.	Genetic and enzymatic analysis of a gene controlling UV sensitivity in Neurospora crassa.	1972
Tuveson, R. W.	Interaction of genes controlling ultraviolet sensitivity in Neurospora crassa.	1972
Tuveson, R. W. , and J. Mangan.	A UV-sensitive mutant of Neurospora defective for photoreactivation.	1970
Worthy, T. E. , and J. L. Epler.	Biochemical basis of radiation-sensitivity in mutants of Neurospora crassa.	1973
Schroeder, A.L.		1986