suppressor-1 of trp-3 allele td201

locus: su(trp-3td201)-1

locus_name: suppressor-1 of trp-3 allele td201

organism_type: B

chromosome_number: VII

chromosome_side: R

link_group: VIIR

cultural_requirements: VIIR. Between met-7 (18%) and arg-10 (7%) (1174). Right of ssu-1 (10 to 13%) (954). Allele specific. Suppresses missense allele td201, but not eight other alleles (td1, td6, td7, td16, td37R, td71, tdl38R, and td141) (1174). Also does not suppress td2, td3, or td24 (910). A suppressed mutant has a low level of tryptophan synthetase activity, allowing slow growth on minimal medium. Enzyme activity is due to a protein physically like the wild-type enzyme (1174, 1175). Strains carrying the suppressor alone, without td201, grow slightly slower than wild type (910). The suppressor is effective when in another nucleus from td201 in a forced heterokaryon between noncomplementing alleles (td16;su plus td2Ol;su+) (910). Called Su-1 or Su-1td201 in reference 954, su-YS in reference 910, and su1(201) in reference 1173.

enzyme_id:

anid_name:

near_l: met-7 (18%)

near_r: arg-10 (7%)

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supplement:

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Strains

FGSC #	Reporting Genes	Species
FGSC #5443	Has been replaced by strain number: 9999	Neurospora crassa

References

Authors	Title	Year
Colburn, R. W. , and E. L. Tatum.	Studies of a phenylalanine-tyrosine requiring mutant of N. crassa (strain S4342).	1965
St. Lawrence, P. , R. Naish, and B. Burr.	The action of suppressors of a tryptophan synthetase mutant of Neurospora inheterocaryons.	1965
Seale, T. W.	Super-suppressors in Neurospora crassa. I. Induction, genetic localization and relationship to a missense suppressor.	1972
Yourno, J. D. , and S. R. Suskind.	Suppressor gene action in the tryptophan synthetase system of Neurospora crassa. I. Geneticstudies.	1964
Yourno, J. D. , and S. R. Suskind.	Suppressor gene action in the tryptophan synthetase system of Neurospora crassa. II. Biochemical studies.	1964