Gene: lysine(122)
lysine(122)
locus: lys(122)
locus_name: lysine(122)
organism_type: B
chromosome_number:
chromosome_side:
link_group:
cultural_requirements: All lysine auxotrophs are inhibited competitively by arginine (287, 288). Resistance to arginine is conferred on lys-1 mutants by a presumed transport mutation argR, q.v. See the arg entry for medium that provides both lysine and arginine requirements. Lysine biosynthesis is by the alpha-aminoadipate pathway in Neurospora and other higher fungi (see reference 1103) (Fig. 16). Complex interactions between lys, pyr, and argmutations have been described (485). Enzymes of lysine biosynthesis are derepressed coordinately with those of arginine, histidine, and tryptophan (1131). See cpc-1.Biosynthetic pathway of lysine, showing sites of gene action of lys-4and lys-5and probable sites of lys-2 and lys-3 gene action (119, 400, 464, 762, 1087). alpha-amino-epsilon-hydroxycaproic acid can be converted to alpha-aminoadipate semialdehyde (1178), but apparently is not an intermediate.
enzyme_id:
anid_name:
near_l:
near_r:
neu_name:
supplement: lysine
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #7361 | Not available; tolC trp-4;lys(122) | Neurospora tetrasperma |
References
