histidine

locus: his

locus_name: histidine

organism_type: B

chromosome_number:

chromosome_side:

link_group:

cultural_requirements: Most histidine auxotrophs are inhibited by complex media or by certain combinations of amino acids with which histidine does not compete effectively for permeases of the basic, neutral, and general amino acid transport systems. A histidine mutant can grow on minimal medium plus histidine in the presence of either a basic amino acid or a competing neutral amino acid, but not in the presence of both (434, 628, 646). Histidine mutants were not obtained in early mutant hunts in which complex media were used, but were recovered on histidine-supplemented minimal medium (434, 595). For general studies, see references 162, 434, and 1123. For details of histidine biosynthesis, see Fig. 14. Enzymes of histidine biosynthesis are derepressed coordinately with those of tryptophan, arginine, and lysine (137, 1131); reviewed in reference 642. See cpc-1. Called hist.

enzyme_id:

anid_name:

near_l:

near_r:

neu_name:

supplement: histidine

image_url:

Strains

FGSC #	Reporting Genes	Species

References

Authors	Title	Year
Carsiotis, M. , and R. F. Jones.	Cross-pathway regulation:tryptophan-mediated control of histidine and arginine biosyntheticenzymes in Neurospora crassa.	1974
Haas, F. , M. B. Mitchell, B. N. Ames, and H. K. Mitchell.	A series of histidineless mutants of Neurospora crassa.	1952
Lein, J. , H. K. Mitchell, and M. B. Houlahan.	A method for selection of biochemical mutants of Neurospora.	1948
Magill, C. W. , H. Sweeney, and V. W. Woodward.	Histidine uptake in strains of Neurospora crassa with normal and mutant transportsystems.	1972
Mathieson, M. J. , and D. G. Catcheside.	Inhibition of histidine uptake in Neurospora crassa.	1955
Wesseling, A. C. , and M. Carsiotis.	Amino acid cross-pathway regulation in Neurospora crassa:involvement of nitrogen-richamino acids.	1974