hydroxamic acid sensitive

locus: has

locus_name: hydroxamic acid sensitive

organism_type: B

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link_group:

cultural_requirements: Not mapped. Unlinked to azs (311).Lacks salicyl hydroxamic acid-sensitive respiratory pathway; cannot produce the hydroxamate-sensitive respiratory pathway when grown in the presence of chloramphenicol. Grows slowly in the presence of antimycin A (311). Double mutant has;azs is unable to grow in the presence of antimycin A; the wild type and the has+;azs single mutant are able to grow well on antimycin A. The double mutant has;azs (called ANT-1: antimycin sensitive) was used to obtain oligomycin-resistant (312) and succinate dehydrogenase-deficient (307) mutants. From strain ANT-1, called alx-1 (308).

enzyme_id:

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Strains

FGSC #	Reporting Genes	Species

References

Authors	Title	Year
Edwards, D. L. , D. M. Belsole, H. J. Guzik, and B. W. Unger.	Selection of succinic dehydrogenase mutants of Neurospora crassa.	1979
Edwards, D. L. , J. H. Chalmers, Jr. , H. J. Guzik, and J. T. Warden.	Assembly of the cyanide-insensitive respiratory pathway inNeurospora crassa.	1976
Edwards, D. L. , and B. W. Unger.	Cyanide- and hydroxamate-resistant respiration in Neurospora crassa.	1978
Edwards, D. L. , and B. W. Unger.	Nuclear mutations conferring oligomycin resistance in Neurospora crassa.	1978