sorbose resistance

locus: sor

locus_name: sorbose resistance

organism_type: B

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cultural_requirements: Sorbose is used to induce colonial growth in platings of Neurospora(109, 239). Resolution is improved if sorbose is used in conjunction with cot-1(165). Numerous sor mutants have been obtained which show spreading growth on concentrations of sorbose that restrict the wild type (e.g., references 560, 561, and 898). With the exception of sor-4, scoring has been on minimal medium plus 0.025% filter-sterilized sorbose. Certain mutants selected in other ways may also be resistant to sorbose. For example, the mutant sor(T9), selected by ability to hydrolyze starch and defective in extracellular amylase, is simultaneously sorbose resistant and osmotic sensitive (710). Sorbose-resistant mutations at four loci act as dominance modifiers of the ascus effect of dominant Pk-2 alleles (898). Most sormutants have probably not been examined for possible pleiotropic amylase or osmotic phenotypes.

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Strains

FGSC #	Reporting Genes	Species

References

Authors	Title	Year
Brockman, H. E. , and F. J. de Serres.	"Sorbose toxicity" in Neurospora.	1963
Catcheside, D. G.	A second gene controlling allelic recombination in N. crassa.	1966
Davis, R. H. , and F. J. de Serres.	Genetic and microbiological research techniques for N. crassa.	1970
Klingmller, W.	Kreuzungs-Analyse Sorboseresistenter Mutanten von Neurospora crassa.	1967
Klingmller, W.	Die Aufnahme der Zucker Sorbose, Fructose, and Glucose durch Sorbose-resistente Mutanten von Neurosporacrassa.	1967
Murayama, T. , and T. Ishikawa.	Mutation in Neurospora crassa affecting some of the extracellular enzymes and several growth characteristics.	1973
Russell, P. J. , and A. M. Srb.	Dominance modifiers in Neurospora crassa:phenocopy selection and influence on certain ascusmutants.	1972