laccase

locus: lacc

locus_name: laccase

organism_type: B

chromosome_number: VII

chromosome_side: L

link_group: VIIL

cultural_requirements: VIIL. Between nic-3 (14%) and thi-3 (7%). Laccase structural gene (benzenediol:oxygen oxidoreductase, urishol oxidase), extracellular. Alleles from wild-type strains TS and OR sequenced. The laccase polypeptide is processed posttranslationally at both its N- and C-termini. lacc mutants do not show a detectable phenotype except that laccase is not produced. Gene expression is induced by inhibitors of RNA or protein synthesis or by certain aromatic molecules. The secreted enzyme forms a blue halo of oxidezed o-tolidine around colonies in test plates. Screening for mutants that overproduced laccase led to the ident. of lah-1. Screening for additional mutants that did not allow the overexpression of laccase in the lah-1 background established that functional cpc-1 was required for lacc induction. Called lni-2.

enzyme_id:

anid_name:

near_l:

near_r:

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #8379	lacc nic-3	Neurospora crassa

References

Authors	Title	Year