locus: nkuA::argB

locus_name:

organism_type: A

chromosome_number:

chromosome_side:

link_group:

cultural_requirements: Arginine requirement. The nkuA gene was deleted in KJ12 by replacing it with argB. This was crossed to A770. TN02A7 is a segregant of this cross. Deletion of the nkuA (the A. nidulans homolog of human Ku70 gene) reduces the frequency of non-homologous integration of transforming DNA and greatly facilitates gene targeting. NkuA deleted strains show no obvious growth defect and are not sensitive to a variety of DNA damaging drugs.

enzyme_id:

anid_name:

near_l:

near_r:

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC A1145	pyrG89; pyroA4; nkuA::argB; riboB2	Aspergillus nidulans
FGSC A1146	wA3; pyroA4; argB2; nkuA::argB	Aspergillus nidulans
FGSC A1147	pyrG89; argB2; pabaB22,nkuA::argB; riboB2	Aspergillus nidulans
FGSC A1148	pyrG89; nkuB::A. fumigatus riboB pyroA4 nkuA::argB; riboB2	Aspergillus nidulans
FGSC A1149	pyrG89; pyroA4 nkuA::argB	Aspergillus nidulans
FGSC A1150	pyroA4 nkuA::argB; riboB2	Aspergillus nidulans

References

Authors	Title	Year