Gene: choline-1 IVR
choline-1
locus: chol-1
locus_name: choline-1
organism_type: B
chromosome_number: IV
chromosome_side: R
link_group: IVR
cultural_requirements: IVR. Linked to ad-6 (1%). probably to the right (633). (482) Requires choline (470). Also uses mono- or dimethylaminoethanol (468) (Fig. 12). Deficient in S-adenosylmethionine:phosphatidylethanolamine-N-methyl transferase (222, 924). Abnormal colonial morphology on limiting choline (222). Colonies from single conidia on minimal agar medium resemble inhibited A/a duplications, with swollen hyphae and darkening in the presence of phenylalanine plus tyrosine (D.D. Perkins, unpublished data). Abnormal phospholipid composition on limited concentrations of supplement (501). Best scored late on minimal medium. Grows slightly and then stops (D.D. Perkins, unpublished data). Used to study inhibition of cytochrome-mediated respiration and of conidiation when lecithin is depleted by choline starvation (534, 535). Initial allele called 34486.
enzyme_id: 37
Enzyme: S-adenosylmethionine:phosphatidylethanolamine-N-methyl transferase
anid_name: choA
near_l: ad-6 (1%) probably to the right
near_r:
neu_name:
supplement: choline
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #485 | chol-1 | Neurospora crassa |
| FGSC #1116 | chol-1 | Neurospora crassa |
| FGSC #2949 | chol-1;chol-2 | Neurospora crassa |
| FGSC #2950 | chol-1;inl | Neurospora crassa |
| FGSC #2982 | chol-1 | Neurospora crassa |
| FGSC #8131 | chol-1 | Neurospora crassa |
| FGSC #10456 | csp-1 his-3+::frq^P-luc; chol-1 ras-1^bd | Neurospora crassa |
| FGSC #10457 | csp-1 his-3+::frq^P-luc; chol-1 ras-1^bd frq7 | Neurospora crassa |
References
