Gene: cyanide insensitive-1
cyanide insensitive-1
locus: cni-1
locus_name: cyanide insensitive-1
organism_type: B
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cultural_requirements: Unmapped chromosomal gene. Not in V (309). No cyanide-sensitive or antimycin A-sensitive respiration in the first 24 h of growth. Also, initially insensitive to salicyl hydroxamic acid. But salicyl hydroxamic acid and cyanide together inhibit (309). Cyanide-insensitive respiration and the cytochrome c level decrease markedly in the late log phase and stationary phase, whereas the cytochrome aa3 level increases rapidly (559). As shown by electron microscopy, mitochondria are defective in the early log phase, but later resemble the wild type (558). Behaves as a cold-sensitive ribosome assembly mutant. Small subunits are not assembled at low temperatures; the respiratory differences between early and late growth noted above were found at 30°C, and normal aa3 production occurred throughout growth at 37°C (548). Electron spin resonance data (308). Selected by failure to reduce tetrazolium in overlay after inositol-less death enrichment (310).
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Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #3232 | cni-1 inl | Neurospora crassa |
References
