chloramphenicol sensitive-1

locus: cpl-1

locus_name: chloramphenicol sensitive-1

organism_type: B

chromosome_number: VI

chromosome_side: L

link_group: VIL

cultural_requirements: VIL. Between ad-8 (6 to 11%) and lys-5 (6%) (180, PB).Sensitive to chloramphenicol (< 0.5 mg/ml added to autoclaved medium) and to antimycin A (1 µg/ml). (The wild type is resistant to 4 mg of chloramphenicol per ml.) Protein synthesis is not grossly altered. Cyanide-insensitive and azide-insensitive respiratory systems are still present. Cytochrome spectrum normal on minimal medium. Obtained by inositol death enrichment and replica-plating, using a strain of genotype inl;trp-3;sn cr-1(180, 182). Scorable on 0.5 mg of chloramphenicol per ml autoclaved in medium (PB).

enzyme_id: 202

Enzyme: none

anid_name: casA

near_l: ad-8 (6 to 11%)

near_r: lys-5 (6%)

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #2459	cpl-1	Neurospora crassa
FGSC #3739	cpl-1	Neurospora crassa

References

Authors	Title	Year
Chalmers, J. H. , Jr.	A novel method of selecting drug-sensitive mutants of N. crassa.	1973
Chalmers, J. H. , and P. St. Lawrence.	cpl-1:A Neurospora mutant sensitive to chloramphenicol.	1979