cold-sensitive ribosome biosynthesis

locus: crib-1

locus_name: cold-sensitive ribosome biosynthesis

organism_type: B

chromosome_number: IV

chromosome_side:

link_group: IV

cultural_requirements: IV. Linked to met-1 (6%) (927). Defective ribosome biosynthesis below 20°C; attributed to a defect in ribosomal ribonucleic acid (rRNA) processing (897). Grows at 6 the wild-type rate at 10°C and 79% at 25°C. 37S cytosolic ribosomal subunits are underaccumulated, and relatively little stable 17S rRNA is produced at low temperatures. Not a conditional lethal mutation (896, 927). Conditionally defective in expression of S-adenosylmethionine synthetase activity (900).

enzyme_id: 202

Enzyme: none

anid_name:

near_l: Linked to met-1 (6%)

near_r:

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #3300	crib-1	Neurospora crassa

References

Authors	Title	Year
Russell, P. J. , J. R. Hammett, and E. U. Selker.	Neurospora crassa cytoplasmic ribosomes:cold-sensitive mutant defective inribosomal ribonucleic acid synthesis.	1976
Russell, P. J. , E. U. Selker, and J. A. Jackson.	Cold-sensitive mutation in Neurospora crassa affecting the production of 17S ribosomalRNA from ribosomal precursor RNA.	1981
Russell, P. J. , and K. Talbot.	S-adenosyl methionine synthetase in a ribosome biosynthesis mutant of Neurospora crassa.	1980
Schlitt, S. C. , and P. J. Russell.	Neurospora crassa cytoplasmic ribosomes:isolation and characterization of a cold-sensitive mutantdefective in ribosome biosynthesis.	1974