ergosterol-3

locus: erg-3

locus_name: ergosterol-3

organism_type: B

chromosome_number: III

chromosome_side: R

link_group: IIIR

cultural_requirements: IIIR. Linked to dow (10 to 14%), probably to the left (PB).The cell membrane is deficient in ergosterol; slightly (2x) increased resistance to nystatin and other polyene antibiotics (417, 418). Biosynthetic lesion not identified (419). Female sterile, but forms tiny protoperithecia. Slow growth, reduced conidiation, uneven production of aerial hyphae.

enzyme_id: 98

Enzyme: delta 14,15 reductase

anid_name:

near_l: Linked to dow (10 to 14%)

near_r:

neu_name:

supplement:

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #2725	erg-3	Neurospora crassa
FGSC #2726	Has been replaced by strain number: 3439	Neurospora crassa
FGSC #3439	erg-3	Neurospora crassa
FGSC #7243	dow erg-3	Neurospora crassa
FGSC #7244	dow erg-3	Neurospora crassa
FGSC #7247	nit-7 erg-3	Neurospora crassa
FGSC #7248	nit-7 erg-3	Neurospora crassa
FGSC #7249	dow erg-3	Neurospora crassa
FGSC #7250	dow erg-3	Neurospora crassa
FGSC #9077	erg-3	Neurospora tetrasperma
FGSC #9078	HYG erg-3 dup	Neurospora tetrasperma
FGSC #9079	HYG erg-3 dup	Neurospora tetrasperma
FGSC #9080	HYG erg-3 dup	Neurospora tetrasperma
FGSC #9081	HYG erg-3 dup	Neurospora tetrasperma
FGSC #9082	HYG erg-3 dup	Neurospora tetrasperma
FGSC #9083	HYG erg-3 dup	Neurospora tetrasperma

References

Authors	Title	Year
Grindle, M.	Sterol mutants of Neurospora crassa:their isolation, growth characteristics and resistance to polyene antibiotics.	1973
Grindle, M.	The efficacy of various mutagens and polyene antibiotics for the induction and isolation of sterol mutants ofNeurospora crassa.	1974
Grindle, M. , and R. Farrow.	Sterol content and enzyme defects of nystatin-resistant mutants of Neurospora crassa.	1978