histidine-4

locus: his-4

locus_name: histidine-4

organism_type: B

chromosome_number: IV

chromosome_side: R

link_group: IVR

cultural_requirements: IVR. Between cot-1 (1 to 4%) and met-5 (4%) (812). (434)Requires histidine (434). Accumulates L-histidinol phosphate. Lacks histidinol phosphate phosphatase (24, 25) (Fig. 14). Allele P143h is heat sensitive (his+ at 25 C); C141 is not (815). Both are leaky (726).

enzyme_id: 117

Enzyme: histidinol phosphate phosphatase

anid_name: none

near_l: cot-1 (1 to 4%)

near_r: met-5 (4%)

neu_name:

supplement: histidine

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #78	Has been replaced by strain number: 2161	Neurospora crassa
FGSC #398	cot-1 his-4	Neurospora crassa
FGSC #989	his-4	Neurospora crassa
FGSC #2161	his-4	Neurospora crassa
FGSC #2162	his-4	Neurospora crassa

References

Authors	Title	Year
Ames, B. N.	The biosynthesis of histidine:L-histidinol phosphate phosphatase.	1957
Ames, B. N.	The biosynthesis of histidine:D-erythro-imidazoleglycerol phosphate dehydrase.	1957
Haas, F. , M. B. Mitchell, B. N. Ames, and H. K. Mitchell.	A series of histidineless mutants of Neurospora crassa.	1952
Murray, N. E. , and M. Glassey.	A second "leaky" histidine mutant in linkage group IV.	1962
Perkins, D. D. , M. Glassey, and B. A. Bloom.	New data on markers and rearrangements in Neurospora.	1962
Perkins, D. D. , and N. E. Murray.	New markers and linkage data.	1963