isoleucine plus valine-3

locus: ilv-3

locus_name: isoleucine plus valine-3

organism_type: B

chromosome_number: IV

chromosome_side: R

link_group: IVR

cultural_requirements: IVR. Linked to met-2 (0/129) (PB). Between leu-2 (4%) and ad-6 (9%) (579).Requires both isoleucine and valine. Accumulates pyruvate. Very low acetohydroxy acid synthetase activity (136) (Fig. 15). Alleles recombine and complement (579, 1112). Markedly inhibited by methionine (PB). Called iv-3; group 4.

enzyme_id: 41

Enzyme: acetohydroxy acid synthetase

anid_name:

near_l: leu-2 (4%), Linked to met-2 (0/129)

near_r: ad-6 (9%)

neu_name:

supplement: isoleucine and valine

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #575	ilv-3	Neurospora crassa
FGSC #1053	ilv-3;lys-1	Neurospora crassa
FGSC #1054	ilv-3;lys-1	Neurospora crassa
FGSC #1055	ilv-3;lys-1	Neurospora crassa
FGSC #1164	ilv-3	Neurospora crassa

References

Authors	Title	Year
Caroline, D. F. , R. W. Harding, H. Kuwana, T. Satyanarayana, and R. P. Wagner.	The iv-3 mutants of N. crassa. II. Activity ofacetohydroxy acid synthetase.	1969
Kuwana, H. , and R. P. Wagner.	The iv-3 mutants of Neurospora crassa. I. Genetic and biochemical characteristics.	1969
Wagner, R. P. , A. Bergquist, T. Barbee, and K. Kiritani.	Genetic blocks in the isoleucine-valine pathway of Neurospora crassa.	1964