Gene: lysine-5 VIL

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lysine-5

locus: lys-5

locus_name: lysine-5

organism_type: B

chromosome_number: VI

chromosome_side: L

link_group: VIL

cultural_requirements: VIL. Right of cyt-2 (6%), aro-6 (3%), and cpl-1 (5 to 7%). Left of un-4 (2%) (1012, PB).Requires lysine. Partial response to glutaric acid (762). Lacks homocitrate synthase activity (464, 762) (Fig. 16). Some alleles such as 37402, called asco, are autonomous ascospore lethals or semilethals, resulting in mostly immature white spores (see reference 1012 for a photograph). Viability of the lys- spores is improved by long incubation (7). With other alleles such as DS6-85, ascospores blacken and germinate normally. Accumulates malate plus citrate on media with limiting lysine concentrations (464). Four complementation groups (12). Allele 37402 called asco.

enzyme_id: 118

Enzyme: homocitrate synthase

anid_name:

near_l: cyt-2 (6%), aro-6 (3%), and cpl-1 (5 to 7%)

near_r: un-4 (2%)

neu_name:

supplement: lysine

image_url:

Strains

FGSC # Reporting Genes Species
FGSC #4lys-5 ylo-1Neurospora crassa
FGSC #139lys-5Neurospora crassa
FGSC #2120Not available; Replaced with 4098; os-4; pan-2Neurospora crassa
FGSC #2127Has been replaced by strain number: 4097Neurospora crassa
FGSC #3251chol-2 ad-8 lys-5 un-4 pan-2Neurospora crassa
FGSC #3252chol-2 ad-8 lys-5 un-4 pan-2Neurospora crassa
FGSC #4097lys-5Neurospora crassa
FGSC #4098lys-5Neurospora crassa
FGSC #5182Not available sn cr-1;chol-2 lys-5 ylo-1 pan-2 trp-2Neurospora crassa
FGSC #5184Not available chol-2 lys-5 ylo-1 pan-2 trp-2Neurospora crassa
FGSC #5185chol-2 lys-5 ylo-1 pan-2Neurospora crassa
FGSC #6458mus(FK128);lys-5Neurospora crassa
FGSC #7214ad-8 lys-5Neurospora crassa
FGSC #7881sn cr-1;mtr;lys-5 trp-2Neurospora crassa
FGSC #7882sn cr-1;mtr uvs-2;lys-5 trp-2Neurospora crassa

References

Authors Title Year
Ahmad, M. , S. Haque, M. U. Ahmad, A. Zaman, M. Mohiuddin, Y. A. Saeed and A. Khairul.Studies on the organization of genes controlling lysine biosynthesis in N. crassa. IV. Segregation patterns, maturity and viability of ascospores and conidiation of some lys-5mutants.1980
Ahmad, M. , A. Mozmadar, A. Baset, M. Fayaz, A. Badrul, M. A. Rahman, and B. Saha.Studies on the organization of genescontrolling lysine biosynthesis in Neurospora crassa. I. Isolation and characterization of lysine mutants belonging to four loci.1977
Hogg, R. W. , and H. P. Broquist.Homocitrate formation in Neurospora crassa. Relation to lysine biosynthesis.1968
Nichoalds, G. E. , M. A. Bromley, and H. P. Broquist.Glutarate and the lysine requirement of Neurospora crassa STL-7.1971
Stadler, D. R.A map of linkage group VI of Neurospora crassa.1956

Neurospora Crassa Wikipedia

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