mutagen sensitive-25

locus: mus-25

locus_name: mutagen sensitive-25

organism_type: B

chromosome_number: VII

chromosome_side: C

link_group: VIIC

cultural_requirements: VIIC. Between met-7(4%, 6%) and un-10. Cloned. Epistasis group Uvs-6. Homologous to yeast RAD54, a gene involved in homologous recombination with sequence conserved from fungi to humans. Two alleles, SA3 and FK123. Both are highly sensitive to histidine, moderately sensitive to MMS, MNNG, and gamma rays, and not sensitive to UV or mitomycin C. At least FK123 is slightly sensitive to bleomycin. Homozygous barren.

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Strains

FGSC #	Reporting Genes	Species
FGSC #6424	mus-25	Neurospora crassa
FGSC #6425	mus-25	Neurospora crassa
FGSC #6426	mus-25 nic-3	Neurospora crassa
FGSC #6427	mus-25 nic-3	Neurospora crassa

References

Authors	Title	Year