Gene: pyrimidine-2 IVR
pyrimidine-2
locus: pyr-2
locus_name: pyrimidine-2
organism_type: B
chromosome_number: IV
chromosome_side: R
link_group: IVR
cultural_requirements: IVR. Right of nit-3 (2 to 9%). Left of mat (3%) and the T(NM152) right breakpoint (633, 812, 1000, PB). (482)Requires uracil or other pyrimidine. Lacks orotidine 5'-monophosphate pyrophosphorylase activity (133, 134) (Fig. 20). Needs medium containing >0.5 mg of uracil per ml for optimal growth. Allele 38502 is leaky. Pyrimidine biosynthetic pathway, showing sites of gene action (134, 456, 841, 1140). Carbamyl phosphate for arginine synthesis is made as a separate pool by a different enzyme system (see arg-2, arg-3, Fig. 10). Interchange between the two pools occurs only in certain mutant combinations. ATP, Adenosine 5'-monophosphate.
enzyme_id: 148
Enzyme: orotidine 5'-monophosphate pyrophosphorylase
anid_name: pyrF
near_l: nit-3 (2 to 9%)
near_r: mat (3%) and the T(NM152) right breakpoint
neu_name:
supplement: uracil or pyrimidine
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #86 | Replaced with 3466 | Neurospora crassa |
| FGSC #161 | pdx-1 pan-1 pyr-2 | Neurospora crassa |
| FGSC #170 | pdx-1 pan-1 pyr-2 | Neurospora crassa |
| FGSC #365 | pyr-2 | Neurospora crassa |
| FGSC #391 | col-4 pyr-2 | Neurospora crassa |
| FGSC #3365 | pyr-2 | Neurospora crassa |
| FGSC #3466 | pyr-2 | Neurospora crassa |
| FGSC #7210 | nit-3 pyr-2 | Neurospora crassa |
| FGSC #7211 | pyr-2 cys-4 | Neurospora crassa |
| FGSC #8397 | pyr-2 | Neurospora crassa |
| FGSC #8398 | pyr-2 | Neurospora crassa |
References
