FGSC #9592

Mutant Type

Genus: N

reporting_genes: Sk-3; leu-3

species: Neurospora crassa

allele: -; R156

stock: DDP 5031-1

glasgow:

mutagen:

Depositor: EGB

Link Group: III; IL

MT: a

Species No: 10

gene_back:

oppmt:

trans:

ref1:

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-9592

Locus	Cultural Requirements	Link Group	Type
leu-3	IL. Right of the In(OY323) left breakpoint and nit-2 (12 to 18%). Left of cyt-1 (5 to 8%) and T(OY321) (57, 816, PB; D.D. Perkins, N.B. Raju, and E.G. Barry, in preparation). (868)Requires leucine (867, 868). Regulatory mutation; prevents synthesis of alpha-isopropylmalate isomerase and beta-isopropylmalate dehydrogenase and prevents full derepression of alpha-isopropylmalate synthetase; also involved in regulation of isoleucine and valine synthesis, q.v. (427, 771, 833) (Fig. 15). The original allele, 47313, is leaky, but some other alleles, e.g., R156, are not.	IL	B
Sk-3	Near the centromere. The killer allele Sk-3K suppresses crossing over in the interval r(Sk-2)-1-leu-1 (29% in controls). Recombines with his-7 (11%) but not with leu-1 (0/72) or acr-7 (0/60,000) and only 3/19,000 with acr-2. (1092; B.C. Turner, personal communication) Origin and characteristics resemble those of Sk-2, q.v. However, Sk-3K strains are sensitive to killing by Sk-2K and vice versa. The killer allele was found in N. intermedia, introgressed into N. crassa. Most wild-type strains of both species are sensitive, but resistant strains of N. intermedia have been found. Strains resistant to Sk-3K are not necessarily resistant to Sk-2K (857, 1092).		B

Neurospora Crassa Wikipedia