FGSC #3903

Mutant Type

Genus: N

reporting_genes: mus-14;al-2;pan-1

species: Neurospora crassa

allele: SC3;15300;5531

stock: M-3-36

glasgow:

mutagen: NG

Depositor: NCM

Link Group: VIL;IR;IVR

MT: a

Species No: 10

gene_back: M

oppmt: 0

trans:

ref1: DeLange & Mishra Genetics 97:247-259 1981, https://doi.org/10.1093/genetics/97.2.247

ref2: DeLange and Mishra Mut. Res. 96:187 1982, https://doi.org/10.1016/0027-5107(82)90086-0

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-3903

ksudc_link_html: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-3903 ↗

Genes

Locus	Cultural Requirements	Link Group	Type
mus-14	VI. Linked to lys-5. Growing mycelia are moderately sensitive to MMS, but conidia are not. Insensitive to UV, X rays, nitroguanidine, and histidine. Poor growth. Homozygous fertile. Spontaneous mutation is reduced. One mutant, SC3.	VI	B
pan-1	IVR. Between ad-6 (1 to 2%) and cot-1 (2 to 3%) (633, 692, PB). (482). cel, col-1, int, pho-3, and thi-5 all appear to be closely linked in this crowded region. Requires intact pantothenic acid for growth under standard conditions. Able to synthesize both precursors, beta-alanine and pantoyl lactone (1058). Ability to synthesize pantothenic acid from beta-alanine plus pantoyl lactone is demonstrable in vitro but not in vivo unless cultures are aerated (1111, 1113, 1114). Unlike pan-2, pan-1 has no effect on ascospore ripening in heterozygous crosses. Called group A. For alleles see reference 138.	IVR	B
al-2	IR. Right of os-5 (<1%) and T(STL76). Left of arg-6(1%) and al-1 (797, 802, 808, 816, 818). Included in duplications from Tp(T54M94), confirming location left of arg-6(808). (482) Carotenoids absent or abnormal, but steroids produced (398). Blocked in microsomal fraction and defective in phytoene synthetase (445), a particulate enzyme (445 and references cited therein) (Fig. 9). Tracer experiments indicate a lesion between prephytoene pyrophosphate and phytoene (572). Alleles include those resulting in white and pale rose-white, e.g., 15300 and Y254MI65 (1042), and purple, e.g., MN58a (154). For complementation, see references 500 and 1041. Fine-structure mapping (500, 1042) needs reevaluation because of new information on the location of the arg-6 marker (797).	IR	B