FGSC #4125

Mutant Type

Genus: N

reporting_genes: pdx-1 pan-1 cys-4

species: Neurospora crassa

allele: 37803 5531 K7

stock: M1071 A

glasgow:

mutagen:

Depositor: EK

Link Group: IVR IVR IVR

MT: A

Species No: 10

gene_back:

oppmt: 4126

trans:

ref1: Kafer 1982. Neurospora Newsl. 29:41-44, https://doi.org/10.4148/1941-4765.1645

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-4125

ksudc_link_html: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-4125 ↗

Genes

Locus	Cultural Requirements	Link Group	Type
cys-4	IVR. Right of mat (10%) and T(NM152). Left of uvs-2(5%) (721, 808, 1023). (815) Uses cysteine; slight response to thiosulfate (721). Poor growth on methionine. Lacks sulfite reductase, as do cys-2 and cys-10 mutants (596).	IVR	B
pan-1	IVR. Between ad-6 (1 to 2%) and cot-1 (2 to 3%) (633, 692, PB). (482). cel, col-1, int, pho-3, and thi-5 all appear to be closely linked in this crowded region. Requires intact pantothenic acid for growth under standard conditions. Able to synthesize both precursors, beta-alanine and pantoyl lactone (1058). Ability to synthesize pantothenic acid from beta-alanine plus pantoyl lactone is demonstrable in vitro but not in vivo unless cultures are aerated (1111, 1113, 1114). Unlike pan-2, pan-1 has no effect on ascospore ripening in heterozygous crosses. Called group A. For alleles see reference 138.	IVR	B
pdx-1	IVR. Right of pyr-1 (<1 to 10%). Left of T(S1229) and pt (2%) (40, 55, 692, 808). (482) Uses pyridoxine, pyridoxal, or pyridoxamine (843, 845, 846). Shows intralocus complementation (845, 846) and recombination (848), Provided the first proven example of gene conversion (686). Scoring is sharpened by addition of 100 mg of desoxypyridoxine per liter (845). Several alleles (called pdxp: e.g., 44602) are pH sensitive and can grow without pyridoxine on medium containing ammonium ions at a pH above 6 (1029). Conidia are subject to death by unbalanced growth on minimal medium (1033). A yellow pigment is excreted under certain conditions by the pdx-1;En(pdx) double mutant; see En(pdx). Allele 44204 originally called pdx-2 (see reference 848).	IVR	B