FGSC #6470

Mutant Type

Genus: N

reporting_genes: mus(FK133);met-1

species: Neurospora crassa

allele: FK133;M105

stock: M2503

glasgow:

mutagen:

Depositor: EK

Link Group: VIC;IVR

MT: A

Species No: 10

gene_back:

oppmt: 6469

trans:

ref1:

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-6470

Locus	Cultural Requirements	Link Group	Type
mus(FK133)			B
met-1	IVR. Right of oxD (3%) and the T(S1229) left breakpoint. Left of col-4 (4%) (55, 158, 718, 768, 808). Uses methionine but not homocysteine (469) (Fig. 17). Lacks methylene tetrahydrofolate reductase and, thus, lacks the coenzyme needed for transmethylating homocysteine (124, 963, 964). A report that the mutant met-1 also lacks cystathionine-gamma-synthase (547) proved incorrect; the error resulted because methyl tetrahydrofolate is an essential activator of cystathionine-gamma-synthase (965). Methylene tetrahydrofolate reductase is feedback-inhibited by S-adenosylmethionine (124). Used in heteroallelic duplications from T(S1229) to assay mitotic recombination (56).	IVR	B

Neurospora Crassa Wikipedia