Gene: arginase VIIR
arginase
locus: aga
locus_name: arginase
organism_type: B
chromosome_number: VII
chromosome_side: R
link_group: VIIR
cultural_requirements: VIIR. Between wc-1 (2%) and arg-10 (24 to 27%) (240, 697). Presumed structural gene for arginase (240, 697) (see Fig. 10). Unable to form ornithine from arginine; arginine is thus unable to satisfy the proline requirement of pro-3 in a pro-3 aga double mutant. Prototrophic single mutants develop polyamine requirement in the presence of arginine. This is due to feedback inhibition of ornithine biosynthesis by arginine, combined with a catabolic block in ornithine formation from arginine (240). Siderophore production is severely reduced in the absence of ornithine in the triple mutant aga arg-5 ota, which has been used to study iron transport (1146, 1147) and to obtain mutants defective in siderophore uptake (G.W. Charlang and N.P. Williams, personal communication); see sit.
enzyme_id: 66
Enzyme: arginase
anid_name: agaA
near_l: wc-1 (2%)
near_r: arg-10 (24 to 27%)
neu_name:
supplement:
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #1698 | aga | Neurospora crassa |
| FGSC #1699 | aga | Neurospora crassa |
| FGSC #2744 | arg-5;ota;aga | Neurospora crassa |
| FGSC #7040 | spe-2;aga | Neurospora crassa |
| FGSC #7041 | spe-2;aga | Neurospora crassa |
| FGSC #7042 | spe-3;aga | Neurospora crassa |
| FGSC #7043 | spe-3;aga | Neurospora crassa |
| FGSC #7920 | esr(BMH8);aga | Neurospora crassa |
| FGSC #7921 | esr-3;aga | Neurospora crassa |
| FGSC #7922 | esr-2;aga | Neurospora crassa |
| FGSC #7923 | esr-1;aga | Neurospora crassa |
| FGSC #7924 | pmb;aga | Neurospora crassa |
| FGSC #7925 | pmb;aga | Neurospora crassa |
| FGSC #8386 | spe-1; aga | Neurospora crassa |
| FGSC #8387 | his-3; aga | Neurospora crassa |
| FGSC #8388 | his-3; aga; spe-1::hph | Neurospora crassa |
| FGSC #8389 | pyr-3 pyr-1; arg-1 arg-6; aga | Neurospora crassa |
| FGSC #8390 | pyr-3 arg-14; aga | Neurospora crassa |
| FGSC #8391 | pyr-3 arg-14; aga | Neurospora crassa |
References
