FGSC #1698

Mutant Type

Genus: N

reporting_genes: aga

species: Neurospora crassa

allele: UM906

stock: agab3R3A (UM

glasgow:

mutagen: UV

Depositor: RHD

Link Group: VIIR

MT: A

Species No: 10

gene_back: M

oppmt: 1699

trans:

ref1: Davis et al 1970 J Bact 102:299-305, https://doi.org/10.1128/jb.102.2.299-305.1970

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-1698

Locus	Cultural Requirements	Link Group	Type
aga	VIIR. Between wc-1 (2%) and arg-10 (24 to 27%) (240, 697). Presumed structural gene for arginase (240, 697) (see Fig. 10). Unable to form ornithine from arginine; arginine is thus unable to satisfy the proline requirement of pro-3 in a pro-3 aga double mutant. Prototrophic single mutants develop polyamine requirement in the presence of arginine. This is due to feedback inhibition of ornithine biosynthesis by arginine, combined with a catabolic block in ornithine formation from arginine (240). Siderophore production is severely reduced in the absence of ornithine in the triple mutant aga arg-5 ota, which has been used to study iron transport (1146, 1147) and to obtain mutants defective in siderophore uptake (G.W. Charlang and N.P. Williams, personal communication); see sit.	VIIR	B

Neurospora Crassa Wikipedia