nicotinic acid

locus: nic

locus_name: nicotinic acid

organism_type: B

chromosome_number:

chromosome_side:

link_group:

cultural_requirements: nic mutants are preferably supplemented with nicotinamide rather than nicotinic acid at most pH values because of permeability (97). nt mutants are best treated as nicmutants for purposes of growth and scoring. For good recovery of some nicmutants from crosses, crossing media should be supplemented with nicotinamide at levels higher (10X) than those required for growth, even when the protoperithecial parent is nic+ (789; P. St. Lawrence, personal communication). See Fig. 18 for the biosynthetic pathway. For regulation, see references 111, 371, 604, and 926.

enzyme_id:

anid_name:

near_l:

near_r:

neu_name:

supplement: nicotinamide

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC A1122	nimG10, chaA, lac, nic	Aspergillus nidulans

References

Authors	Title	Year
Bonner, D. M. , and G. W. Beadle.	Mutant strains of Neurospora requiring nicotinamide or related compounds for growth.	1946
Perkins, D. D.	New markers and multiple point linkage data in Neurospora.	1959