Gene: chain elongation IVR

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chain elongation

locus: cel

locus_name: chain elongation

organism_type: B

chromosome_number: IV

chromosome_side: R

link_group: IVR

cultural_requirements: IVR. Linked to pan-1 (1%) and cot-1 (0/17) (812). Requires saturated fatty acids. Defect attributed to impaired chain elongation (455). Deficient in the fatty acid synthetase complex (317). increased sensitivity to oligomycin (L.R. Forman and S. Brody, cited in reference 293), Tween 20 provides a convenient supplement. Requirement is "leaky" at 21 to 22°C (317) but not at 34°C (812). Used to change fatty acid composition (113) and make the circadian clock sensitive to fatty acids and temperature (114, 649). Temperature compensation of the clock is lacking in celmutants (650). Used to study membrane lipid-phase transitions and electrical properties (363, 364). Used to incorporate photolabile azido fatty acid probes for membrane studies (176). Called ol (oleic acid) (812) and fas (fatty acid synthesis) (317). Initial report of oleic acid utilization (812) was incorrect (455), probably because of impurities.

enzyme_id: 202

Enzyme: none

anid_name:

near_l: Linked to pan-1 (1%) and cot-1 (0/17)

near_r:

neu_name:

supplement: tween 20

image_url:

Strains

FGSC # Reporting Genes Species
FGSC #165Has been replaced by strain number: 6783Neurospora crassa
FGSC #819celNeurospora crassa
FGSC #2947bd celNeurospora crassa
FGSC #3484csp-1;cel bdNeurospora crassa
FGSC #5411celNeurospora crassa
FGSC #5412celNeurospora crassa
FGSC #6783celNeurospora crassa

References

Authors Title Year
Brody, S. , and B. Allen.The effects of branched chain fatty acid incorporation into N. crassa membranes.1972
Brody, S. , and S. A. Martins.Circadian rhythms in N. crassa:effects of unsaturated fatty acids.1979
Chakravarti, D. N. , B. Chakravarti, and P. Chakrabarti.Incorporation of photolabile azido fatty acid probes in N. crassa andSaccharomyces cerevisae.1981
Dunn-Coleman, N. S. , E. A. Robey, A. B. Tomsett, and R. H. Garrett.Glutamate synthase levels in Neurospora crassa mutants alteredwith respect to nitrogen metabolism.1981
Elovson, J.Purification and properties of the fatty acid synthetase complex from Neurospora crassa, and the nature of the fas-mutation.1975
Freidman, K. J.Role of lipids in the Neurospora crassa membrane. I. Influence of fatty acid composition on membrane lipid phasetransitions.1977
Friedman, K. J.Role of lipids in the Neurospora crassa membrane. II. Membrane potential and resistance studies; the effect of alteredfatty acid composition on the electrical properties of the cell membrane.1977
Henry, S. A. , and A. D. Keith.Saturated fatty acid requirer of Neurospora crassa.1971
Mattern, D. , and S. Brody.Circadean rhythms in Neurospora crassa:effects of saturated fatty acids.1979
Mattern, D. L. , L. R. Forman, and S. Brody.Circadean rhythms in Neurospora crassa:A mutation affecting temperaturecompensation.1982
Perkins, D. D. , M. Glassey, and B. A. Bloom.New data on markers and rearrangements in Neurospora.1962

Neurospora Crassa Wikipedia

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