acetate-4

locus: ace-4

locus_name: acetate-4

organism_type: B

chromosome_number: IV

chromosome_side: L

link_group: IVL

cultural_requirements: IVL. Between cys-10 (19 to 33%) and fi (10 to 17%) (578). Requires acetate. Grows on complex complete medium (578). Lacks pyruvate dehydrogenase complex activity. Lipoate acetyltransferase fails to aggregate to form the core of the pyruvate dehydrogenase complex. As a result, there is high activity of the free components pyruvate dehydrogenase and lipoamide reductase (769). Not the same as ac-4of reference 1034.

enzyme_id: 130

Enzyme: lipoate acetyltransferase

anid_name: pdhA

near_l: cys-10 (19 to 33%)

near_r: fi (10 to 17%)

neu_name:

supplement: acetate

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #3472	ace-4	Neurospora crassa
FGSC #3473	ace-4	Neurospora crassa
FGSC #8212	ace-4	Neurospora crassa

References

Authors	Title	Year
Kuwana, H. , and R. Okumura.	Genetics and some characteristics of acetate-requiring strains in Neurospora crassa.	1979
Okumura, R. , and H. Kuwana.	Gene-protein relationships in acetate-requiring mutants of Neurospora crassa deficient in activity ofpyruvate dehydrogenase complex.	1979
Kuwana & Okumura		1979