lysine-2

locus: lys-2

locus_name: lysine-2

organism_type: B

chromosome_number: V

chromosome_side: R

link_group: VR

cultural_requirements: VR. Right of ilv-1 (4 to 7%). Left of cyh-2 (<1%) and leu-5 (9%) (3, 818, 839). (399)Requires lysine. Will not use epsilon-hydroxynorleucine (400). Probably blocked in conversion of alpha-aminoadipate semialdehyde to saccharopine (1087) (Fig. 16). Initial allele: 37101.

enzyme_id: 202

Enzyme: none

anid_name:

near_l: ilv-1 (4 to 7%)

near_r: cyh-2 (<1%) and leu-5 (9%)

neu_name:

supplement: lysine

image_url:

Strains

FGSC #	Reporting Genes	Species
FGSC #241	lys-2 pk ad-7;ylo-1	Neurospora crassa
FGSC #1127	lys-2	Neurospora crassa
FGSC #2163	lys-2	Neurospora crassa
FGSC #2164	lys-2	Neurospora crassa
FGSC #7255	cyh-2 lys-2 leu-5 mei-2	Neurospora crassa

References

Authors	Title	Year
Ahmad, M. , M. U. Ahmad, and A. Zaman.	Mapping of locus lysine-2 in N. crassa.	1966
Good, N.	Lysine metabolism in Neurospora.	1951
Good, N. , R. Heilbronner, and H. K. Mitchell.	epsilon-Hydroxynorleucine as a substitute for lysine for Neurospora.	1950
Perkins, D. D. , M. R. Smith, and D. R. Galeazzi.	New markers and linkage data.	1973
Printz, D. B. , and S. R. Gross.	An apparent relationship between mistranslation and an altered leucyl-tRNA synthetase in aconditional lethal mutant of Neurospora crassa.	1967
Trupin, J. S. , and H. P. Broquist.	Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. 1. Studies inNeurospora crassa.	1965