oligomycin resistant

locus: oli

locus_name: oligomycin resistant

organism_type: B

chromosome_number: VII

chromosome_side: R

link_group: VIIR

cultural_requirements: VIIR. Between met-9 (8 to 24%) and arg-11 (3 to 16%) (960). Linked to frq-1 (<2%) and possibly allelic (282, 283). (959) Resistant to oligomycin. Defective in energy transduction (313). Structural gene for dicyclohexylcarbodiimide-binding proteolipid (subunit 9) of F0 portion of mitochondrial adenosine triphosphate synthetase (958). The amino acid sequence (81 residues) (959) shows extensive homology with the corresponding proteolipid in yeast, in which, in contrast to Neurospora, it is the product of a mitochondrial gene (960, 1109). Specific single amino acid substitutions have been identified for three mutants (959). oli mutants are selected effectively by using double mutant azs; has (called ANT-1), which is deficient in both salicyl hydroxamic acid-sensitive and azide-sensitive alternate oxidase pathways. Scored on 5 µg of oligomycin per ml of liquid medium, 3 days, 30°C (312). Altered period of circadian rhythm cosegregates and reverts with oli (282, 283).

enzyme_id: 16

Enzyme: ATP synthetase

anid_name: oliC

near_l: met-9 (8 to 24%)

near_r: arg-11 (3 to 16%); Linked to frq-1 (<2%)

neu_name:

supplement:

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