FGSC #506

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Reporting Genes: sfo

Species: crassa

Allele: E18829(d)

Alternate Strain Number: 18558-5(24-7

Depositor: RWB

Linkage Group: VIIC

Mating Type: a

Species Number: 10

Genetic Background: M

Opposite Mating Type: 576

ref1: Emerson and Emerson 1951 Microb Genet Bull 4: 7-9 E12

ref2: Reissig, JL 1952 PhD thesis CA Institute of Technology R42, https://thesis.library.caltech.edu/10688/1/Reissig_JL_1952.pdf

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
sfo	Linked to the centromere (<1%) (318), between thi-3 (6%) (874) and hlp-1(1 to 9%) (458). Requires sulfonamide at 35°C and is stimulated by sulfonamide at lower temperatures (319). Overproduces p-aminobenzoic acid; hence, growth is inhibited by exogenous p-aminobenzoic acid (1179). For sfo;pab-1 double mutant on minimal medium plus sulfonamide, p-amino-benzoic acid is stimulatory at very low concentrations but inhibitory at higher (319). For sfo;met-1 double mutant on minimal medium plus sulfonamide, methionine is stimulatory at very low concentrations but inhibitory at higher (1180). Best tested on solid minimal medium growth tubes at 35°C. Suppressor mutations occur frequently (318).	VII	B