FGSC #651

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Reporting Genes: sfo

Species: crassa

Allele: E15172(d)

Depositor: MJM

Linkage Group: VIIC

Mating Type: A

Species Number: 10

Genetic Background: M

Opposite Mating Type: 652

ref1: Barratt et al. 1956. J. Bacteriol. 71:108-114, https://doi.org/10.1128/JB.71.1.108-114.1956

ref2: Emerson 1947. J. Bacteriol. 54:195-207, https://doi.org/10.1128/JB.54.2.195-207.1947

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
sfo	Linked to the centromere (<1%) (318), between thi-3 (6%) (874) and hlp-1(1 to 9%) (458). Requires sulfonamide at 35°C and is stimulated by sulfonamide at lower temperatures (319). Overproduces p-aminobenzoic acid; hence, growth is inhibited by exogenous p-aminobenzoic acid (1179). For sfo;pab-1 double mutant on minimal medium plus sulfonamide, p-amino-benzoic acid is stimulatory at very low concentrations but inhibitory at higher (319). For sfo;met-1 double mutant on minimal medium plus sulfonamide, methionine is stimulatory at very low concentrations but inhibitory at higher (1180). Best tested on solid minimal medium growth tubes at 35°C. Suppressor mutations occur frequently (318).	VII	B