FGSC #990

Mutant Type

Genus: N

reporting_genes: trp-2

species: Neurospora crassa

allele: S4266

stock: S4266

glasgow:

mutagen: UV

Depositor: LG

Link Group: VIR

MT: A

Species No: 10

gene_back: M

oppmt: 4364

trans:

ref1: Barratt et al 1954 Adv Genet 6:1-93, https://doi.org/10.1016/s0065-2660(08)60127-3

ref2: https://www.genetics.org/content/genetics/56/3/413.full.pdf; https://www.genetics.org/content/genetics/41/4/528.full.pdf

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-990

Locus	Cultural Requirements	Link Group	Type
trp-2	VIR. Right of del (0 to 13%). Left of un-23 (5 to 27%), T(OY320), and ws-1 (38%) (818, 822, 1019, PB). Uses kynurenine, anthranilic acid, indole, or tryptophan (96). Kynurenine is utilized by conversion to anthranilate (447). Inferred to be the structural gene for the alpha subunit of the anthranilate synthetase complex (546). The gene product catalyzes anthranilate synthesis with ammonia but not with glutamine as the amino donor (29). Specifies anthranitate synthetase (glutamine linked) in collaboration with trp-1 in trifunctional trp-1+-trp-2+ enzyme aggregate (181, 259) (Fig. 11); see trp-1. Nonsense allele used to isolate supersuppressors (954) and to study enzyme complex restored by supersuppressors (183).	VIR	B

Neurospora Crassa Wikipedia