tryptophan-2

locus: trp-2

locus_name: tryptophan-2

organism_type: B

chromosome_number: VI

chromosome_side: R

link_group: VIR

cultural_requirements: VIR. Right of del (0 to 13%). Left of un-23 (5 to 27%), T(OY320), and ws-1 (38%) (818, 822, 1019, PB). Uses kynurenine, anthranilic acid, indole, or tryptophan (96). Kynurenine is utilized by conversion to anthranilate (447). Inferred to be the structural gene for the alpha subunit of the anthranilate synthetase complex (546). The gene product catalyzes anthranilate synthesis with ammonia but not with glutamine as the amino donor (29). Specifies anthranitate synthetase (glutamine linked) in collaboration with trp-1 in trifunctional trp-1+-trp-2+ enzyme aggregate (181, 259) (Fig. 11); see trp-1. Nonsense allele used to isolate supersuppressors (954) and to study enzyme complex restored by supersuppressors (183).

enzyme_id: 65

Enzyme: anthranilate synthetase

anid_name: trpA

near_l: del (0 to 13%)

near_r: un-23 (5 to 27%), T(OY320), and ws-1 (38%)

neu_name:

supplement: anthranillic acid or indole or tryptophan or kynurenine

image_url:

Strains

References