FGSC #2926

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Reporting Genes: Has been replaced by strain number: 3313

Species: crassa

Allele: T54M50(t) P616 45302

Alternate Strain Number: 9208

Depositor: DDP

Mating Type: A

Species Number: 10

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
dow	IIIR. Right of ty-1 (21%) and un-17 (23%); linked to erg-3 (10%) and acu-7(0/72) (816).Soft, matty growth, conidiating and covering slants (816). An excellent marker: good viability, fertility, and scorability.	IIIR	B
un-15	IIR. Linked to rip-1 (1%). Right of trp-3 (10%). (813, PB). Unknown function. Heat sensitive, 34°C versus 25°C (T. Ishikawa, personal communication). Grows poorly at the permissive temperature; rip-1 is, therefore, preferred to un-15 as a marker for the right end of II (811). One allele, T54M50.	IIR	B
trp-2	VIR. Right of del (0 to 13%). Left of un-23 (5 to 27%), T(OY320), and ws-1 (38%) (818, 822, 1019, PB). Uses kynurenine, anthranilic acid, indole, or tryptophan (96). Kynurenine is utilized by conversion to anthranilate (447). Inferred to be the structural gene for the alpha subunit of the anthranilate synthetase complex (546). The gene product catalyzes anthranilate synthesis with ammonia but not with glutamine as the amino donor (29). Specifies anthranitate synthetase (glutamine linked) in collaboration with trp-1 in trifunctional trp-1+-trp-2+ enzyme aggregate (181, 259) (Fig. 11); see trp-1. Nonsense allele used to isolate supersuppressors (954) and to study enzyme complex restored by supersuppressors (183).	VIR	B