FGSC #2198

Mutant Type

Genus: N

reporting_genes: uc-3

species: Neurospora crassa

allele: RW203

stock:

glasgow:

mutagen: UV

Depositor: LGW

Link Group:

MT: a

Species No: 10

gene_back: M

oppmt: 0

trans:

ref1: Williams and Mitchell 1969. J. Bact. 100:383-389, https://doi.org/10.1128/jb.100.1.383-389.1969

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-2198

Locus	Cultural Requirements	Link Group	Type
uc-3	Unmapped. Thymidine salvage pathway defect (Fig. 23). Unable to use thymidine, thymine, or hydroxy-methylcytosine, but can use deoxyuridine, 5-formyluracil, uracil, or uridine to support growth of pyr-4 when uc-1 is also present. Excretes thymine into the medium when grown in the presence of thymidine (1141). Lacks thymine 7-hydroxylase, which catalyzes the reactions thymine -> 5-hydroxymethyluracil -> 5-formyluracil -> uracil-5-carboxylic acid; apparently, there is an alternate enzyme for 5-formyluracil -> uracil-5-carboxylic acid, which explains the growth on 5-formyluracil (616, 977).		B

Neurospora Crassa Wikipedia