FGSC #7218

Mutant Type

Genus: N

reporting_genes: nic-3 thi-3

species: Neurospora crassa

allele: Y31881 18558

stock: 7145

glasgow:

mutagen:

Depositor: DDP

Link Group: VIIL VIIL

MT: A

Species No: 10

gene_back:

oppmt: 7219

trans:

ref1:

ref2:

site:

country:

ksudc_link: https://digital.lib.k-state.edu/item/neurospora-crassa/fgsc-7218

Locus	Cultural Requirements	Link Group	Type
nic-3	VIIL. Right of spco-4 (1%) and do (3%). Left of thi-3 (9 to 27%) and csp-2 (16 to 22%) (539, 812, 816, PB). (M.K. Allen, cited in references 718 and 789) Uses nicotinic acid, nicotinamide, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, or high concentrations of quinolinic acid (96, 1168). Accumulates alpha-N-acetylkynurenine; blocked in conversion of kynurenine to 3-hydroxykynurenine (1168) (Fig. 18). Pyridine nucleotide levels (111). Pathway from tryptophan to nicotinic mononucleotide, showing sites of gene action (96, 100, 368, 1168). The enzymatic reactions between 3-hydroxyanthranilate and nicotinic mononucleotide have not been demonstrated directly in Neurospora.	VIIL	B
thi-3	VIIL. Between nic-3 (9 to 18%) and T(T54M50) (808, 812, 816). (482). Uses thiamine or thiazole (1059). Does not undergo growth adaptation on minimal medium. Growth on minimal medium is leaky at first, but becomes tight with exhaustion of endogenous thiazole (302), so scoring is best done late.	VIIL	B

Neurospora Crassa Wikipedia