Gene: nicotinic acid-3 VIIL
nicotinic acid-3
locus: nic-3
locus_name: nicotinic acid-3
organism_type: B
chromosome_number: VII
chromosome_side: L
link_group: VIIL
cultural_requirements: VIIL. Right of spco-4 (1%) and do (3%). Left of thi-3 (9 to 27%) and csp-2 (16 to 22%) (539, 812, 816, PB). (M.K. Allen, cited in references 718 and 789) Uses nicotinic acid, nicotinamide, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, or high concentrations of quinolinic acid (96, 1168). Accumulates alpha-N-acetylkynurenine; blocked in conversion of kynurenine to 3-hydroxykynurenine (1168) (Fig. 18). Pyridine nucleotide levels (111). Pathway from tryptophan to nicotinic mononucleotide, showing sites of gene action (96, 100, 368, 1168). The enzymatic reactions between 3-hydroxyanthranilate and nicotinic mononucleotide have not been demonstrated directly in Neurospora.
enzyme_id: 202
Enzyme: none
anid_name:
near_l: spco-4 (1%) and do (3%)
near_r: thi-3 (9 to 27%) and csp-2 (16 to 22%)
neu_name:
supplement: nicotinamide or nicotinic acid or3-hydroxyanthranillicacid or 3-hydroxykynurenine or quinolinic acid
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