Gene: nicotinic acid-3 VIIL

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nicotinic acid-3

locus: nic-3

locus_name: nicotinic acid-3

organism_type: B

chromosome_number: VII

chromosome_side: L

link_group: VIIL

cultural_requirements: VIIL. Right of spco-4 (1%) and do (3%). Left of thi-3 (9 to 27%) and csp-2 (16 to 22%) (539, 812, 816, PB). (M.K. Allen, cited in references 718 and 789) Uses nicotinic acid, nicotinamide, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, or high concentrations of quinolinic acid (96, 1168). Accumulates alpha-N-acetylkynurenine; blocked in conversion of kynurenine to 3-hydroxykynurenine (1168) (Fig. 18). Pyridine nucleotide levels (111). Pathway from tryptophan to nicotinic mononucleotide, showing sites of gene action (96, 100, 368, 1168). The enzymatic reactions between 3-hydroxyanthranilate and nicotinic mononucleotide have not been demonstrated directly in Neurospora.

enzyme_id: 202

Enzyme: none

anid_name:

near_l: spco-4 (1%) and do (3%)

near_r: thi-3 (9 to 27%) and csp-2 (16 to 22%)

neu_name:

supplement: nicotinamide or nicotinic acid or3-hydroxyanthranillicacid or 3-hydroxykynurenine or quinolinic acid

image_url:

Strains

FGSC # Reporting Genes Species
FGSC #121Has been replaced by strain number: 2246Neurospora crassa
FGSC #129Has been replaced by strain number: 2247Neurospora crassa
FGSC #152nic-3 met-7Neurospora crassa
FGSC #153nic-3 met-7Neurospora crassa
FGSC #154nic-3 wc-1Neurospora crassa
FGSC #156nic-3 wc-1Neurospora crassa
FGSC #157nic-3 wc-1 arg-10Neurospora crassa
FGSC #254fr;nic-3Neurospora crassa
FGSC #260ro-3;nic-3Neurospora crassa
FGSC #261ro-3;nic-3Neurospora crassa
FGSC #302Has been replaced by strain number: 1195Neurospora crassa
FGSC #1541cys-10;nic-3Neurospora crassa
FGSC #1542cys-10;nic-3Neurospora crassa
FGSC #2073nic-3 wc-1 skNeurospora crassa
FGSC #2074nic-3 wc-1 skNeurospora crassa
FGSC #2246Has been replaced by strain number: 4081Neurospora crassa
FGSC #2247Has been replaced by strain number: 4082Neurospora crassa
FGSC #2514csp-1;nic-3Neurospora crassa
FGSC #2516csp-2 nic-3Neurospora crassa
FGSC #2517csp-2 nic-3Neurospora crassa
FGSC #2520csp-2 nic-3Neurospora crassa
FGSC #2528nic-3Neurospora crassa
FGSC #3132T(VII->IV)T54M50,het-e nic-3Neurospora crassa
FGSC #3235fs-1;nic-3Neurospora crassa
FGSC #3236fs-1;nic-3Neurospora crassa
FGSC #3238fs-2;pan-2;nic-3Neurospora crassa
FGSC #3239fs-3;nic-3Neurospora crassa
FGSC #3241fs-4;nic-3Neurospora crassa
FGSC #3243fs-5;nic-3Neurospora crassa
FGSC #3872csp-2 nic-3Neurospora crassa
FGSC #4081nic-3Neurospora crassa
FGSC #4082nic-3Neurospora crassa
FGSC #4141nic-3 met-7 arg-10Neurospora crassa
FGSC #4142nic-3 met-7 arg-10Neurospora crassa
FGSC #4199uvs-6;nic-3Neurospora crassa
FGSC #4451thi-4;nic-3;ars-1Neurospora crassa
FGSC #4452arg-5;thi-4;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4453arg-5;thi-4;pyr-1;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4458thi-4;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4459thi-4;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4462arg-5;pyr-1;nic-3;ars-1Neurospora crassa
FGSC #4463arg-5;pyr-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4464lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4466pyr-1;nic-3;ars-1Neurospora crassa
FGSC #4467pyr-1;nic-3;ars-1Neurospora crassa
FGSC #4469thi-4;lys-1;nic-3;ars-1Neurospora crassa
FGSC #4470inl;nic-3;ars-1Neurospora crassa
FGSC #4471nic-3;ars-1Neurospora crassa
FGSC #4472un-2;thi-4;nic-3;ars-1Neurospora crassa
FGSC #4473un-2;thi-4;inl;nic-3;ars-1Neurospora crassa
FGSC #4474un-2;thi-4;lys-1;inl;nic-3Neurospora crassa
FGSC #4477un-2;thi-4;nic-3Neurospora crassa
FGSC #4478un-2;arg-5;pyr-1;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4479un-2;arg-5;pyr-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4482un-2;arg-5;nic-3;ars-1Neurospora crassa
FGSC #4483un-2;arg-5;thi-4;pyr-1;nic-3;ars-1Neurospora crassa
FGSC #4486arg-5;thi-4;lys-1;nic-3;ars-1Neurospora crassa
FGSC #4487arg-5;thi-4;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #4488un-2;arg-5;thi-4;pyr-1;lys-1;inl;nic-3;ars-1Neurospora crassa
FGSC #5196sn cr-1;cyh-2 al-3 inl;nic-3 met-7 arg-10Neurospora crassa
FGSC #5197cyh-2 al-3 inl;nic-3 met-7 arg-10Neurospora crassa
FGSC #5198cyh-2 al-3 inl;nic-3 met-7 arg-10Neurospora crassa
FGSC #5199rip-1;acr-2 dow;ylo-1;nic-3 arg-10Neurospora crassa
FGSC #5200rip-1;acr-2 dow;ylo-1;nic-3 arg-10Neurospora crassa
FGSC #5210lys-1;ylo-1 pan-2;nic-3 met-7Neurospora crassa
FGSC #5211sn cr-1;lys-1 cyh-2;ylo-1 pan-2;nic-3Neurospora crassa
FGSC #5215sn cr-1;lys-1;ylo-1 pan-2;nic-3 met-7Neurospora crassa
FGSC #5217This strain is not available sn cr-1;nic-3 met-7 arg-10Neurospora crassa
FGSC #5888mei-2;nic-3Neurospora crassa
FGSC #5889mei-2;nic-3Neurospora crassa
FGSC #6426mus-25 nic-3Neurospora crassa
FGSC #6427mus-25 nic-3Neurospora crassa
FGSC #6951Mauriceville-1c rDNA inl;al-2;nic-3Neurospora crassa
FGSC #7218nic-3 thi-3Neurospora crassa
FGSC #7219nic-3 thi-3Neurospora crassa
FGSC #7220(nic-3 wc-1 sk a + a[m1] ad-3B cyh-1)Neurospora crassa
FGSC #7257nic-3 oli;inl inv mei-2Neurospora crassa
FGSC #7580cyt-7 nic-3Neurospora crassa
FGSC #7581(cyt-7 nic-3 + a[m1] ad-3B cyh-1)Neurospora crassa
FGSC #8305nic-1; nic-3 ars-1Neurospora crassa
FGSC #8306nic-1; nic-3 ars-1Neurospora crassa
FGSC #8378his-3+::tk+ cyh-1; Bml[r]; inl; nic-3 a[m33]Neurospora crassa
FGSC #8379lacc nic-3Neurospora crassa
FGSC #8408nic-1; nic-3 ars-1Neurospora crassa
FGSC #8409nic-2; nic-3 ars-1Neurospora crassa

References

Authors Title Year
Bonner, D. M.The identification of a natural precursor of nicotinic acid.1948
Bonner, D. M. , and C. Yanofsky.Quinolinic acid accumulation in the conversion of 3-hydroxyanthranilic acid to niacin inNeurospora.1949
Brody, S.Regulation of pyridine nucleotide levels and ratios in Neurospora crassa.1972
Gaertner, F. H.A response to a letter from David Perkins concerning the question of whether nt mutants involve tryptophanpyrrolase.1981
Kafer, E. , and E. Perlmutter.Isolation and genetic analysis of MMS-sensitive mus mutants of Neurospora.1980
Murray, N. E.The distribution of methionine loci in Neurospora crassa.1960
Perkins, D. D.New markers and multiple point linkage data in Neurospora.1959
Perkins, D. D. , M. Glassey, and B. A. Bloom.New data on markers and rearrangements in Neurospora.1962
Perkins, D. D. , D. Newmeyer, C. W. Taylor, and D. C. Bennett.New markers and map sequences in Neurospora crassa, with adescription of mapping by duplication coverage, and of multiple translocation stocks for testing linkage.1969
Yanofsky, C. , and D. M. Bonner.Evidence for the participation of kynurenine as a normal intermediate in the biosynthesis of niacinin Neurospora.1950

Neurospora Crassa Wikipedia

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