Gene: methionine-7 VIIR
methionine-7
locus: met-7
locus_name: methionine-7
organism_type: B
chromosome_number: VII
chromosome_side: R
link_group: VIIR
cultural_requirements: VIIR. Right of qa-2 (<1%), ars (<1%), and the centromere (one second-division ascus in several hundred). Left of met-9 (10[-4]) and wc-1 (1 to 4%) (146, 725; M.E. Case, personal communication). (718; M.K. Allen, cited in references 718 and 789) Uses cystathionine, homocysteine, or methionine (718; N. H. Horowitz, cited in reference 1180). Lacks cystathionine-gamma-synthase (547) (Fig. 17). This enzyme is also lacking in the mutant met-3 (547). See met-3 for regulation. Apparently contiguous with met-9by coconversion. Flanking markers are recombined in most met-7+ met-9+ recombinants (725). Functionally distinct from the mutant met-9, which has active cystathionine-gamma-synthase (547) but cannot use homocysteine. No mutants lacking both functions have been isolated. Allele NM251 is suppressible by supersuppressor RN33 (same as ssu-1?) (725). Allele K79 is inseparable from reciprocal translocation T(I;VII)K79 (808).
enzyme_id: 89
Enzyme: cystathionine-g-synthase
anid_name: metB
near_l: qa-2 (<1%), ars (<1%), and the centromere
near_r: met-9 and wc-1(1-4%)
neu_name:
supplement: methionine or cystathionine or homocysteine
image_url: